DISTRIBUTION STUDIES ON RADIOACTIVE Hg$sup 203$ SODIUM MERCAPTOMERIN IN ANIMALS
Journal Article
·
· Proc. Soc. Exptl. Biol. Med.
Using Hg/sup 203/ labeled mercaptomerin sodium and studying radioautographs and renal distribution, 91.7% of an intramuscularly injected dose of 1 mg Hg/kg was found in the kidney of the rat within the first hour with maximum concentration occurring in the cortical area. Radioactivity was detected for 28 days in plasma and in renal tissue. Intravenous administration of radioactive mercaptomerin sodium resulted in a rapid decline in plasma concentration during the first 5 minutes. Rate of urinary excretion appears to be a function of anterial plasma-renal vein plasma difference. (auth)
- Research Organization:
- Hahnemann Medical Coll., Philadelphia
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-007196
- OSTI ID:
- 4177397
- Journal Information:
- Proc. Soc. Exptl. Biol. Med., Journal Name: Proc. Soc. Exptl. Biol. Med. Vol. Vol: 103
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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