A Note on Induced Sterility in Mink

Journal Article · Fri Feb 01 04:00:00 EST 1963 · Reproduction (Cambridge)

DOI:https://doi.org/10.1530/jrf.0.0050083· OSTI ID:4177307

VENGE, O.

In an attempt to induce mutations in mink, 30 males (Royal Pastel or Standard type) were exposed to x rays. The testes of three groups of 10 males each were irradiated one, two, or three times with a dose of 500 r at each treatment. The irradiation caused a very high degree of sterility in all three groups, and when the males were bred to nonirradiated females, a clear dose effect was observed. After 1500 r, no spermatozoa were found in the vaginal secretions immediately after copulation. The dose effect could also be seen from the histological results. In the 1500-r group, histological examination revealed extreme degeneration of spermatogenic tissue; spermatogonia, primary and secondary spermatocytes, and spermatids disappeared. In the 1000-r group a similar picture was seen. After 500 r, the damage was less drastic, but a high degree of degeneration was induced. Spermatozoa were found in the lumen in some tubules, but the number of spermatids was extremely low. The induced sterility seen here was very similar to the sterility in homozygous Stewart mink. The similarity between the histological preparations from Stewart mink and males in the present report receiving 1000 and 1500 r was striking, but in the Stewart mink the libido is not affected at all. It is concluded that irradiation of the testicles of mink at a dose of 500 r will cause a low fertility that is close to sterility. (BBB)

• Research Organization: Royal Agricultural Coll. of Sweden, Uppsala
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-000083
• OSTI ID: 4177307
• Journal Information: Reproduction (Cambridge), Journal Name: Reproduction (Cambridge) Journal Issue: 1 Vol. 5; ISSN 1470-1626
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ANIMAL CELLS
ANIMALS
BIOLOGY AND MEDICINE
BODY
GAMMA RADIATION
GENETICS
GONADS
MEASURED VALUES
MEDICINE
MUTATIONS
NUMERICALS
PERSONNEL
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIATION PROTECTION
RADIOTHERAPY
RADIUM
REMOTE HANDLING
REPRODUCTION
SAFETY
STANDARDS
STERILIZATION
X RADIATION