THE EFFECT OF IONIZING RADIATION OF VARIOUS INTENSITY ON REGENERATIVE PROCESS IN THE BONE TISSUE

Journal Article · Wed Jul 01 04:00:00 EDT 1959 · Byull. Eksptl'. Biol. Med.

OSTI ID:4176970

Pilshchik, E M

S> Single Co/sup 60/ gamma irradiation of white rats in doses of 1,000 and 1,500 r caused a distinct depression of regeneration following trepanation of the femur (the medial third of its diaphysis) by means of a dental drill N. 3 (on the 7th to l4th day after the operation). Retarted bone formation could be also observed with the injury of the bone inflicted 3 months after the irradiation (1,000 r). In experiments with chroric irradiation lasting 12 days (the sum total doses being 1,000 and 1,500 r), the efficacy of the radiation action on the bone tissue would not diminish after 2 to 3 months and at times appear to be even somewhat higher. in chronic irradiation the bone marrow tissue showed only slight injuries, but became acutely disturbed following single irradiation. Its structure, however, was rapidly restored. (auth)

• Research Organization: Pavlov Leningrad Medical Inst.
• NSA Number: NSA-14-007241
• OSTI ID: 4176970
• Journal Information: Byull. Eksptl'. Biol. Med., Journal Name: Byull. Eksptl'. Biol. Med. Vol. Vol: 48, No. 7
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BIOLOGY AND MEDICINE
BONE MARROW
BONES
COBALT 60
GAMMA RADIATION
RADIATION DOSES
RADIATION INJURIES
RATS
RECOVERY
REGENERATION