SOME CHANGES IN THE CARBOHYDRATE METABOLISM AND THE ALBUMIN FRACTION OF THE BLOOD SERUM OF RABBITS IN CASE OF CHRONIC TREATMENT WITH IRON-59

Journal Article · Mon Jan 01 04:00:00 EST 1962 · Materialy po Toksikol. Radioaktivn. Veshchestv, Inst. Gigieny Truda i Profzabolevanii Akad. Med. Nauk SSSR

OSTI ID:4146324

Orlyanskaya, R L

A study was undertaken to determine the effect of chronic daily poisoning of rabbits with Fe/sup 59/on the sugar content of the blood, the albumin fraction, and the total albumin content after treatment with glucose. The results indicated that daily administration of 1 and 10 mu C/kg of body weight of Fe/sup 59/ for a total of 16 months causes only a slight change in the level of the blood sugar; only a chronic exposure to the higher dose resulted in a slight reduction in the sugar level. These animals also exhibited a tendency toward hypoglycemia. No changes were noted in the total albumin content of the serum. Exposure to the higher dose for 6 months caused a reduction of the albumin fraction and a corresponding increase of the globulin content. The A/G ratio was found to decrease first, followed by an increase after a few months. (TTT)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-18-006648
• OSTI ID: 4146324
• Journal Information: Materialy po Toksikol. Radioaktivn. Veshchestv, Inst. Gigieny Truda i Profzabolevanii Akad. Med. Nauk SSSR, Journal Name: Materialy po Toksikol. Radioaktivn. Veshchestv, Inst. Gigieny Truda i Profzabolevanii Akad. Med. Nauk SSSR Vol. Vol: No. 3
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ALBUMINS
BIOLOGY AND MEDICINE
BLOOD SERUM
CARBOHYDRATES
GLUCOSE
IRON 59
METABOLISM
RABBITS
RADIATION EFFECTS
SUGARS
VARIATIONS