Synthesis of Diphosphopyridine Nucleotide in Irradiated Rats
Synthesis of diphosphopyridine nucleotide in vivo following injection of nicotinannide was not abolished when rats were exposed to x radiation in doses up to 1,500 r at 3 to 60 min before the injection. Since the synthesis of this nucleotide is restricted to the nucleus of the cell and requires adenosine triphosphate, this suggests that appreciable amounts of adenosine triphosphate are still available to the cell nuclei during the first 2 or 3 hr after irradiation. (M.C.G.)
- Research Organization:
- Atomic Energy of Canada, Ltd., Chalk River, Ont.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-025339
- OSTI ID:
- 4142891
- Journal Information:
- Nature (London), Journal Name: Nature (London) Journal Issue: 4743 Vol. 187; ISSN 0028-0836
- Publisher:
- Nature Publishing Group
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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