STUDIES ON PROTECTIVE AGENT AGAINST RADIATION HAZARD. II. PROTECTIVE AGENTS AGAINST $gamma$-RAYS. PART I

Journal Article · Thu Jan 01 04:00:00 EST 1959 · Rikagaku Kenkyusho Hokoku (Japan)

OSTI ID:4044519

Namiki, M

The survival rates of mice after gamma irradiation were studied. It was found that a dose of 1000 r was LD/sub 1//sub 0//sub 0/ after 10 days of observation, and the biological effect of gamma rays was about 70% that of x rays. Cysteamine HCl, glutathione, inositol, isoleucine, agmatine, tryptamine, delta -mercapto-n-valerylhydrazide, ascorbic acid, cysteine, and thiouracil were tested for their protective action against radiation hazard. Glutathione was initially effective then suddenly decreased in its effectiveness and showed no change when compared with that of the control group. Tryptamine was the most effective substance. isoLeucine, agmatine, and vitamin C were fairly effective. (Abstr. Japan Med., 1: No. 2, 1960)

• Research Organization: Inst. of Physical and Chemical Research, Tokyo
• NSA Number: NSA-15-022176
• OSTI ID: 4044519
• Journal Information: Rikagaku Kenkyusho Hokoku (Japan), Journal Name: Rikagaku Kenkyusho Hokoku (Japan) Vol. Vol: 35: No. 2; ISSN RKKHA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AMINES
AMINO ACIDS
ASCORBIC ACID
BIOLOGY AND MEDICINE
CYSTEAMINE
CYSTEINE
DRUGS
GAMMA RADIATION
GLUTATHION
LETHAL DOSE
LIFETIME
MICE
ORGANIC SULFUR COMPOUNDS
RADIATION PROTECTION
SUGARS
THIOLS
THIOURACIL
TRYPTAMINES
VITAMINS