DYNAMIC CHARACTERISTICS OF PROTEOLYSIS OF ORGANS WITH HETEROGENIC CELL STRUCTURE DUE TO RADIATION LESION

Journal Article · Sun Jan 01 04:00:00 EST 1961 · Vopr. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr.

OSTI ID:4022615

Mkrtchyan, R G

Some dynamic characteristics of proteolytic process changes in the spleen of white rats were studied. The experiments were conducted on the animals irradiated with x ray doses of 600 and 800 r. Proteolysis was indicated by the change in the amino nitrogen content in the spleen homogenates incubated at 37 deg C during 6 hr. In the spleen of the intact animals the processes of proteolysis develop continuously. In the course of the reaction after the third hour of incubation a plateau of about 2-hr duration is recorded, after which period the reaction is intensified again. The presence of the plateau in the course of the proteolytic reactions in the spleen of the irradiated animals seems to be due to unequal radiosensitivity of the spleen cells. A direct relation between the irradiation dose and the intensity of proteolytic processes in the spleen is disclosed. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-18-019744
• OSTI ID: 4022615
• Journal Information: Vopr. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr., Journal Name: Vopr. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr. Vol. Vol: 2
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

AMINES
ANIMAL CELLS
BIOCHEMISTRY
BIOLOGY AND MEDICINE
DECOMPOSITION
DIAGRAMS
IRRADIATION
METABOLISM
NITROGEN
PROTEINS
PROTEOLYSIS
QUALITATIVE ANALYSIS
RADIATION DOSES
RADIATION INJURIES
RADIOSENSITIVITY
RATS
REACTION KINETICS
SPLEEN
STANDARDS
SUSPENSIONS
TEMPERATURE
VARIATIONS
X RADIATION