The Protective Effects of β-Aminoethylisothiuronium · Br · HBr and p-Aminopropiophenone against Acute Sublethal Whole-Body X-Irradiation in Dogs
Mongrel dogs were subjected to intermittent exposures of 265 or 200 m of whole-body x irradiation. Prior to each radiation insult, experimental animals were given AET, PAPP, or a combination of the two drugs. In the group that received 265-r exposures, dogs given both AET and PAPP tolerated an average of 3268 r per dog; those given AET and PAPP singly had averages of 1413 and 1506 r, respectively. Controls tolerated an average of 707 r each. In the animals subjected to 200 r intermittently, the average accumulated doses were 3550 r for the drug combimation, 2000 r for AET, 2066 r for PAPP, and 866 r for the controls. (auth)
- Research Organization:
- Univ. of Tennessee, Memphis
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-18-019795
- OSTI ID:
- 4021748
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Journal Issue: 4 Vol. 21; ISSN 0033-7587
- Publisher:
- Radiation Research Society
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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