THE EFFECT OF IONIZING RADIATIONS ON THE ANTIGENIC PROPERTIES OF TISSUES

Journal Article · Wed Feb 01 04:00:00 EST 1961 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4005899

Shevlev, A S

Until only recently the effect of ionizing radiations on the antigenic properties of tissues has been studied primarily by means of the reaction of active anaphylsxis with desen sitization. This problem was investigated by subjecting white mice to supralethal (3 to 5000 r) doses of gamma and x-ray radiation and studying the precipitation reaction in the gel. The mice were phlebotomized prior to death and after washing the organs in vivo and in vitro with glacial physiological solution, rabbits were immunized with their serum. The animals presented Oucherlon's precipitation reaction in the gel. The serum of the animals immunized with liver tissue had a higher precipitin level against the homologous tissue of irradiated animals than the level of antibody found in the reaction with the liver tissue of normal mice. According to the results the antigenic properties of the tissue may be modified not only in the terminal stages of radiation sickness but even during the first hours after irradiation. (TTT)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-15-019174
• OSTI ID: 4005899
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 6: No. 2; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANTIBODIES
ANTIGENS
BIOLOGY AND MEDICINE
BLOOD SERUM
GAMMA RADIATION
IMMUNITY
LETHAL DOSE
LIVER
MICE
RABBITS
RADIATION EFFECTS
RADIATION SICKNESS
TISSUES
X RADIATION