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Title: Omics-Lethal Human Viruses, Influenza A Experiment IM101

Dataset ·
ORCiD logo [1]; ORCiD logo [2]; ORCiD logo [1]
  1. Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
  2. Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department
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The purpose of this experiment was to evaluate the host mouse response to wild-type Influenza A/Vietnam/1203/2004 (H5N1) virus, Influenza A/California/04/2009 (H1N1) virus, and Influenza A/Vietnam/1203/2004 (H5N1; "PB2-627E" and "NS1trunc124") infection. Sample data was obtained from whole mouse lung and processed for transcriptomics expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific Influenza A virus host infection.

Research Organization:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)
Contributing Organization:
Modeling Host Responses to Understand Severe Human Virus Infections Program Project
DOE Contract Number:
AC05-76RL01830
OSTI ID:
1661917
Report Number(s):
IM101; NCBI BioProject: PRJNA287214 (mRNA); NCBI BioProject: PRJNA287215 (miRNA); GEO Series: GSE69945 (mRNA); GEO Series: GSE69944 (miRNA)
Availability:
rc-support@pnnl.gov
Country of Publication:
United States
Language:
English

References (1)

Hypergraph models of biological networks to identify genes critical to pathogenic viral response journal May 2021

Cited By (1)

PNNL DataHub Project Omics-LHV Profiling of Host Response to Influenza Infection Post-Processed Data Package DOIs dataset January 2021

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Related Subjects

59 BASIC BIOLOGICAL SCIENCES
Virology [edam.topic:0781]
Immune Response [GO:0006955]
Mus musculus [NCBITAXON:10090]
Influenza A virus [NCBITAXON:11320]
Time Sampled Measurement Datasets [IAO:0000584]
Omics [edam.topic:3391]
Gene expression profile data [edam.data:0928]
BioProject Accession Number [NCIT:C175890]
data transformation [SIO:000594]
differential expression analysis [SWO:7000018]
Data Download [schema:DataDownload]