Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Omics-Lethal Human Viruses, Influenza A Experiment IM103

Dataset ·
 [1];  [2];  [3]
  1. Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Pacific Northwest National Laboratory, Biological Sciences Division
  2. Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department
  3. Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
+ Show Author Affiliations

The purpose of this experiment was to evaluate the host response to wild-type Influenza A/Vietnam/1203/2004 (H5N1; "VN1203") virus infection and mock infection. Sample data was obtained for mouse lung tissue and processed for mRNA, miRNA, proteomics, lipidomics, and metabolomics expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, lipidomics, and transcriptomics dataset download each have a direct relationship to a primary sample submission corresponding to a specific Influenza A virus infection.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)
Contributing Organization:
Modeling Host Responses to Understand Severe Human Virus Infections Program Project
DOE Contract Number:
AC05-76RL01830
OSTI ID:
1661919
Report Number(s):
IM103; NCBI BioProject: PRJNA292023 (mRNA, miRNA); GEO Series: GSE71759 (mRNA, miRNA); MassIVE: MSV000080027 (lipidome); MassIVE: MSV000079469 (proteome); MassIVE: MSV000079327 (metabolome)
Availability:
rc-support@pnnl.gov
Country of Publication:
United States
Language:
English

References (1)

Hypergraph models of biological networks to identify genes critical to pathogenic viral response journal May 2021

Cited By (1)

PNNL DataHub Project Omics-LHV Profiling of Host Response to Influenza Infection Post-Processed Data Package DOIs dataset January 2021

Similar Records

Omics-Lethal Human Viruses, Influenza A Experiment ICL103
Dataset · Sun Jan 17 23:00:00 EST 2021 · OSTI ID:1661913
Omics-Lethal Human Viruses, Influenza A Experiment IM101
Dataset · Sun Jan 17 23:00:00 EST 2021 · OSTI ID:1661917
Omics-Lethal Human Viruses, Influenza A Experiment IM102
Dataset · Sun Jan 17 23:00:00 EST 2021 · OSTI ID:1661918

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
BioProject Accession Number [NCIT:C175890]
Data Download [schema:DataDownload]
Gene expression profile data [edam.data:0928]
Immune Response [GO:0006955]
Influenza A virus [NCBITAXON:11320]
Mass spectrometry data [edam.data:2536]
MassIVE dataset identifier [MS:1002487]
Multi-omics [edam.topic:4021]
Mus musculus [NCBITAXON:10090]
Omics [edam.topic:3391]
Time Sampled Measurement Datasets [IAO:0000584]
Virology [edam.topic:0781]
data transformation [SIO:000594]
differential expression analysis [SWO:7000018]