Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization

Meadows, Corey W.; Kang, Aram; Lee, Taek S.

doi:10.1002/biot.201600433

Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization

Journal Article · Fri Jul 21 00:00:00 EDT 2017 · Biotechnology Journal

DOI:https://doi.org/10.1002/biot.201600433· OSTI ID:1437002

^[1]; Kang, Aram ^[1]; ^[1]

Joint BioEnergy Inst. (JBEI), Emeryville, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Research on renewable biofuels produced by microorganisms has enjoyed considerable advances in academic and industrial settings. As the renewable ethanol market approaches maturity, the demand is rising for the commercialization of more energy-dense fuel targets. Many strategies implemented in recent years have considerably increased the diversity and number of fuel targets that can be produced by microorganisms. Moreover, strain optimization for some of these fuel targets has ultimately led to their production at industrial scale. In this review, we discuss recent metabolic engineering approaches for augmenting biofuel production derived from alcohols, isoprenoids, and fatty acids in several microorganisms. In addition, we discuss successful commercialization ventures for each class of biofuel targets.

View Accepted Manuscript (DOE)

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)

Grant/Contract Number:: AC02-05CH11231

OSTI ID:: 1437002

Alternate ID(s):: OSTI ID: 1377945

Journal Information:: Biotechnology Journal, Journal Name: Biotechnology Journal Journal Issue: 1 Vol. 13; ISSN 1860-6768

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

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