Variants of cellobiohydrolases

Bott, Richard R.; Foukaraki, Maria; Hommes, Ronaldus Wilhelmus; Kaper, Thijs; Kelemen, Bradley R.; Kralj, Slavko; Nikolaev, Igor; Sandgren, Mats; Van Lieshout, Johannes Franciscus Thomas; Van Stigt Thans, Sander

Variants of cellobiohydrolases

Patent · Tue Apr 10 00:00:00 EDT 2018

OSTI ID:1434527

Bott, Richard R.; Foukaraki, Maria; Hommes, Ronaldus Wilhelmus; Kaper, Thijs; Kelemen, Bradley R.; Kralj, Slavko; Nikolaev, Igor; Sandgren, Mats; Van Lieshout, Johannes Franciscus Thomas; Van Stigt Thans, Sander

Disclosed are a number of homologs and variants of Hypocrea jecorina Ce17A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

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Research Organization:: DANISCO US INC, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FC36-08GO18078

Assignee:: DANISCO US INC (CA)

Patent Number(s):: 9,938,551

Application Number:: 14/650,285

OSTI ID:: 1434527

Country of Publication:: United States

Language:: English

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