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Monte Carlo simulation of proton track structure in biological matter

Journal Article · · European Physical Journal. D, Atomic, Molecular, Optical and Plasma Physics
 [1];  [1];  [2];  [1];  [1];  [1];  [3];  [4]
  1. CONICET - Univ. Nacional de Rosario, EKF Rosario (Argentina)
  2. Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
  3. Univ. de Lorraine, Metz (France)
  4. Univ. de Bordeaux, Gradignan (France)

Here, understanding the radiation-induced effects at the cellular and subcellular levels remains crucial for predicting the evolution of irradiated biological matter. In this context, Monte Carlo track-structure simulations have rapidly emerged among the most suitable and powerful tools. However, most existing Monte Carlo track-structure codes rely heavily on the use of semi-empirical cross sections as well as water as a surrogate for biological matter. In the current work, we report on the up-to-date version of our homemade Monte Carlo code TILDA-V – devoted to the modeling of the slowing-down of 10 keV–100 MeV protons in both water and DNA – where the main collisional processes are described by means of an extensive set of ab initio differential and total cross sections.

Research Organization:
Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)
Sponsoring Organization:
USDOE National Nuclear Security Administration (NNSA)
Grant/Contract Number:
AC04-94AL85000
OSTI ID:
1369447
Alternate ID(s):
OSTI ID: 22676826
Report Number(s):
SAND2016-11437J; 649062
Journal Information:
European Physical Journal. D, Atomic, Molecular, Optical and Plasma Physics, Journal Name: European Physical Journal. D, Atomic, Molecular, Optical and Plasma Physics Journal Issue: 5 Vol. 71; ISSN 1434-6060
Publisher:
SpringerCopyright Statement
Country of Publication:
United States
Language:
English

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Cited By (4)

Proton transport modeling in a realistic biological environment by using TILDA-V journal October 2019
Fragment and cluster ions from gaseous and condensed pyridine produced under electron impact journal January 2018
Neutral hydrogen versus proton-induced ionization in water vapor journal October 2019
Many particle spectroscopy of atoms, molecules, clusters and surfaces: international conference MPS-2016 journal July 2017

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