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TILDA-V: A full-differential code for proton tracking in biological matter

Journal Article · · Journal of Physics. Conference Series
 [1];  [2];  [3];  [2];  [2];  [2];  [1]
  1. Univ. de Bordeaux, Gradignan (France)
  2. Univ. Nacional de Rosario, Rosario (Argentina)
  3. Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Understanding the radiation-induced effects at the cellular level is of prime importance for predicting the fate of irradiated biological organisms. Thus, whether it is in radiobiology to identify the DNA critical lesions or in medicine to adapt the radio-therapeutic protocols, an accurate knowledge of the numerous interactions induced by charged particles in living matter is required. Monte-Carlo track-structure simulations represent the most suitable and powerful tools, in particular for modelling the full slowing-down of the ionizing particles in biological matter. Furthermore more of the existing codes are based on semi-empirical cross sections as well as the use of water as surrogate of the biological matter.

Research Organization:
Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)
Sponsoring Organization:
USDOE National Nuclear Security Administration (NNSA)
Grant/Contract Number:
AC04-94AL85000
OSTI ID:
1239384
Alternate ID(s):
OSTI ID: 22537292
Report Number(s):
SAND2016-0496J; 618680
Journal Information:
Journal of Physics. Conference Series, Journal Name: Journal of Physics. Conference Series Journal Issue: 3 Vol. 635; ISSN 1742-6588
Publisher:
IOP PublishingCopyright Statement
Country of Publication:
United States
Language:
English

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