Vesicular Disease in 9-Week-Old Pigs Experimentally Infected with Senecavirus A

Montiel, Nestor; Buckley, Alexandra; Guo, Baoqing; Kulshreshtha, Vikas; VanGeelen, Albert; Hoang, Hai; Rademacher, Christopher; Yoon, Kyoung-Jin; Lager, Kelly

doi:10.3201/eid2207.151863

Vesicular Disease in 9-Week-Old Pigs Experimentally Infected with Senecavirus A

Journal Article · Fri Jul 01 00:00:00 EDT 2016 · Emerging Infectious Diseases

DOI:https://doi.org/10.3201/eid2207.151863· OSTI ID:1285779

Montiel, Nestor ^[1]; Buckley, Alexandra ^[2]; Guo, Baoqing ^[3]; Kulshreshtha, Vikas ^[2]; VanGeelen, Albert ^[2]; Hoang, Hai ^[3]; Rademacher, Christopher ^[3]; Yoon, Kyoung-Jin ^[3]; Lager, Kelly ^[2]

United States Dept. of Agriculture, Ames, IA (United States); United States Dept. of Agriculture, Ames, IA (United States)
United States Dept. of Agriculture, Ames, IA (United States)
Iowa State Univ. College of Veterinary Medicine, Ames, IA (United States)

Senecavirus A has been infrequently associated with vesicular disease in swine since 1988. However, clinical disease has not been reproduced after experimental infection with this virus. Here we report vesicular disease in 9-week-old pigs after Sencavirus A infection by the intranasal route under experimental conditions.

View Accepted Manuscript (DOE)

Research Organization:: United States Dept. of Agriculture, Ames, IA (United States)

Sponsoring Organization:: USDOE

Grant/Contract Number:: AC05-06OR23100

OSTI ID:: 1285779

Journal Information:: Emerging Infectious Diseases, Journal Name: Emerging Infectious Diseases Journal Issue: 7 Vol. 22; ISSN 1080-6040

Publisher:: Centers for Disease Control and PreventionCopyright Statement

Country of Publication:: United States

Language:: English

References (12)

The early pathogenesis of foot-and-mouth disease in pigs infected by contact: a quantitative time-course study using TaqMan RT–PCR Oleksiewicz, Martin B.; Alexandersen, Soren; Donaldson, Alex I. Journal of General Virology, Vol. 82, Issue 4 https://doi.org/10.1099/0022-1317-82-4-747	journal	April 2001
Identification and Complete Genome of Seneca Valley Virus in Vesicular Fluid and Sera of Pigs Affected with Idiopathic Vesicular Disease, Brazil Vannucci, F. A.; Linhares, D. C. L.; Barcellos, D. E. S. N. Transboundary and Emerging Diseases, Vol. 62, Issue 6 https://doi.org/10.1111/tbed.12410	journal	September 2015
Foot-and-Mouth Disease Grubman, M. J.; Baxt, B. Clinical Microbiology Reviews, Vol. 17, Issue 2 https://doi.org/10.1128/cmr.17.2.465-493.2004	journal	April 2004
Structural Features of the Seneca Valley Virus Internal Ribosome Entry Site (IRES) Element: a Picornavirus with a Pestivirus-Like IRES Willcocks, M. M.; Locker, N.; Gomwalk, Z. Journal of Virology, Vol. 85, Issue 9 https://doi.org/10.1128/jvi.01107-10	journal	February 2011
Foot-and-mouth disease viral loads in pigs in the early, acute stage of disease Murphy, C.; Bashiruddin, J. B.; Quan, M. Veterinary Record, Vol. 166, Issue 1 https://doi.org/10.1136/vr.b5583	journal	January 2010
Foot-and-Mouth Disease Richelet, Juan E. The Veterinary Journal (1900), Vol. 84, Issue 9 https://doi.org/10.1016/s0372-5545(17)42063-3	journal	September 1928
Foot-and-Mouth Disease B., W. Nature, Vol. 113, Issue 2841 https://doi.org/10.1038/113537a0	journal	April 1924
Complete genome sequence analysis of Seneca Valley virus-001, a novel oncolytic picornavirus Hales, L. M.; Knowles, N. J.; Reddy, P. S. Journal of General Virology, Vol. 89, Issue 5 https://doi.org/10.1099/vir.0.83570-0	journal	May 2008
Senecavirus A : An Emerging Vesicular Infection in Brazilian Pig Herds Leme, R. A.; Zotti, E.; Alcântara, B. K. Transboundary and Emerging Diseases, Vol. 62, Issue 6 https://doi.org/10.1111/tbed.12430	journal	September 2015
Foot-and-Mouth Disease Grubman, M. J.; Baxt, B. Clinical Microbiology Reviews, Vol. 17, Issue 2 https://doi.org/10.1128/CMR.17.2.465-493.2004	journal	April 2004
Structural Features of the Seneca Valley Virus Internal Ribosome Entry Site (IRES) Element: a Picornavirus with a Pestivirus-Like IRES Willcocks, M. M.; Locker, N.; Gomwalk, Z. Journal of Virology, Vol. 85, Issue 9 https://doi.org/10.1128/JVI.01107-10	journal	February 2011
Foot-and-Mouth Disease Al-Alo K. Z., K. Unpublished https://doi.org/10.13140/rg.2.2.34162.56009	text	January 2019

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A Novel Live Attenuated Vaccine Candidate Protects Against Heterologous Senecavirus A Challenge Sharma, Bishwas; Fernandes, Maureen H. V.; de Lima, Marcelo Frontiers in Immunology, Vol. 10 https://doi.org/10.3389/fimmu.2019.02660	journal	November 2019
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The First Identification and Complete Genome of Senecavirus A Affecting Pig with Idiopathic Vesicular Disease in China Wu, Q.; Zhao, X.; Bai, Y. Transboundary and Emerging Diseases, Vol. 64, Issue 5 https://doi.org/10.1111/tbed.12557	journal	August 2016
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A new wave of Seneca Valley virus outbreaks in Brazil Leme, Raquel A.; Miyabe, Flavia M.; Dall Agnol, Alais M. Transboundary and Emerging Diseases, Vol. 66, Issue 3 https://doi.org/10.1111/tbed.13151	journal	February 2019
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An indirect enzyme-linked immunosorbent assay for the identification of antibodies to Senecavirus A in swine Dvorak, Cheryl M. T.; Akkutay-Yoldar, Zeynep; Stone, Suzanne R. BMC Veterinary Research, Vol. 13, Issue 1 https://doi.org/10.1186/s12917-017-0967-x	journal	December 2016

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