Radiation-induced micrencephaly in guinea pigs
The effect of x rays on brain weight of guinea pig pups at birth was studied for 21-day old embroys exposed in utero to doses of 75 and 100 mGy. When compared to controls and when corrected for body weight, gestation time, litter size, sex, and examiner differences the brains of irradiated pups weighed approximately 46 mg less than those of controls (p<0.001) for the 75-mGy group and about 55 mg less for the 100-mGy group. Brains of females weighed 51 mg less than those of males of the same body weight. Dam weight and caging conditions had no observed effect on brain weight.
- Research Organization:
- Texas Univ., Houston, TX (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG05-89ER60912
- OSTI ID:
- 10184152
- Report Number(s):
- DOE/ER/60912--T1; ON: DE93002866
- Country of Publication:
- United States
- Language:
- English
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