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Title: Positron emission tomographic imaging of tumors using monoclonal antibodies. Progress report, April 15, 1992--October 31, 1992

Technical Report ·
DOI:https://doi.org/10.2172/10168353· OSTI ID:10168353

This research project is developing methods for utilizing positron emission tomography (PET) to increase the clinical potential of radiolabeled monoclonal antibodies (MAbs). This report describes the development of methods for labeling MAbs and their fragments with positron-emitting halogen nuclides, fluorine-18 and iodine-124. These nulides were selected because of the widespread availability of F-18 and because of our extensive experience in the development of new protein radiohalogenation methods.

Research Organization:
Duke Univ. Medical Center, Durham, NC (United States). Dept. of Radiology
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
FG05-89ER60789
OSTI ID:
10168353
Report Number(s):
DOE/ER/60789-4; ON: DE92018599
Resource Relation:
Other Information: PBD: Aug 1992
Country of Publication:
United States
Language:
English