Fundamental limits of positron emission mammography
We explore the causes of performance limitation in positron emission mammography cameras. We compare two basic camera geometries containing the same volume of 511 keV photon detectors, one with a parallel plane geometry and another with a rectangular geometry. We find that both geometries have similar performance for the phantom imaged (in Monte Carlo simulation), even though the solid angle coverage of the rectangular camera is about 50 percent higher than the parallel plane camera. The reconstruction algorithm used significantly affects the resulting image; iterative methods significantly outperform the commonly used focal plane tomography. Finally, the characteristics of the tumor itself, specifically the absolute amount of radiotracer taken up by the tumor, will significantly affect the imaging performance.
- Research Organization:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Organization:
- USDOE Director, Office of Science. Office of Biological and Environmental Research. Medical Sciences Division; National Institutes of Health (US)
- DOE Contract Number:
- AC03-76SF00098
- OSTI ID:
- 835336
- Report Number(s):
- LBNL-48131; R&D Project: 445001; TRN: US0500026
- Journal Information:
- Nuclear Instruments and Methods A, Vol. 497, Issue 1; Other Information: Submitted to Nuclear Instruments and Methods A, Volume 497, No.1; Journal Publication Date: 01/21/2003; PBD: 1 Jun 2001
- Country of Publication:
- United States
- Language:
- English
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