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Positron emission mammography imaging

Journal Article · · Nuclear Instruments and Methods
OSTI ID:832756

This paper examines current trends in Positron Emission Mammography (PEM) instrumentation and the performance tradeoffs inherent in them. The most common geometry is a pair of parallel planes of detector modules. They subtend a larger solid angle around the breast than conventional PET cameras, and so have both higher efficiency and lower cost. Extensions to this geometry include encircling the breast, measuring the depth of interaction (DOI), and dual-modality imaging (PEM and x-ray mammography, as well as PEM and x-ray guided biopsy). The ultimate utility of PEM may not be decided by instrument performance, but by biological and medical factors, such as the patient to patient variation in radiotracer uptake or the as yet undetermined role of PEM in breast cancer diagnosis and treatment.

Research Organization:
Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA (US)
Sponsoring Organization:
USDOE Director. Office of Science. Biological and Environmental Research. Medical Science Division; National Institutes of Health. National Cancer Institute Grant R01-CA67911 (US)
DOE Contract Number:
AC03-76SF00098
OSTI ID:
832756
Report Number(s):
LBNL--53855
Journal Information:
Nuclear Instruments and Methods, Journal Name: Nuclear Instruments and Methods Journal Issue: 1-2 Vol. 525; ISSN NUIMAL; ISSN 0029-554X
Country of Publication:
United States
Language:
English