Optical device for in-line and real-time monitoring of microorganisms

Kacira, Murat; Jia, Fei; Ogden, Kimberly L.; Ogden, Gregory E.

Title: Optical device for in-line and real-time monitoring of microorganisms

Patent · Tue Mar 01 00:00:00 EST 2022

OSTI ID:1892660

Kacira, Murat; Jia, Fei; Ogden, Kimberly L.; Ogden, Gregory E.

A multi-wavelength laser diode based optical sensor system capable of monitoring the dynamics and physiological changes of a microorganism culture in real-time. The microorganism culture from a microorganism production chamber is pumped to a flow chamber. Laser diodes emit light at certain wavelengths through the flow chamber, which is sensed by photodiodes. A laser control circuitry is operatively connected to the laser diodes and a signal conditioning circuitry is operatively connected to the photodiodes. A microprocessor reads and records voltage signals corresponding to the wavelengths. A data acquisition system converts said voltage signals into measurements of biological parameters, which are displayed on a graphical user interface and allow a user to monitor the measurements in real time.

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Research Organization:: Univ. of Arizona, Tucson, AZ (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: EE0006269

Assignee:: Arizona Board of Regents on Behalf of the University of Arizona (Tucson, AZ)

Patent Number(s):: 11,261,474

Application Number:: 15/739,467

OSTI ID:: 1892660

Resource Relation:: Patent File Date: 06/29/2016

Country of Publication:: United States

Language:: English

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