Hypertension: the missing WNKs
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July 2016 |
WNKs are potassium-sensitive kinases
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May 2021 |
Properties of WNK1 and Implications for Other Family Members
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July 2005 |
Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress
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December 2006 |
WNK1, a Novel Mammalian Serine/Threonine Protein Kinase Lacking the Catalytic Lysine in Subdomain II
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May 2000 |
DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering
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January 2009 |
Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis
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January 2016 |
Database Search Algorithm for Identification of Intact Cross-Links in Proteins and Peptides Using Tandem Mass Spectrometry
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July 2010 |
WNK kinases, a novel protein kinase subfamily in multi-cellular organisms
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September 2001 |
Protein hydration: Investigation of globular protein crystal structures
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June 2017 |
Determination of the regularization parameter in indirect-transform methods using perceptual criteria
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August 1992 |
Generation of WNK1 knockout cell lines by CRISPR/Cas-mediated genome editing
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February 2015 |
Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences
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June 2008 |
Interactions among HAMP Domain Repeats Act as an Osmosensing Molecular Switch in Group III Hybrid Histidine Kinases from Fungi
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February 2010 |
BioXTAS RAW : improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis
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September 2017 |
PRIMUS: a Windows PC-based system for small-angle scattering data analysis
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September 2003 |
WNK pathways in cancer signaling networks
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November 2018 |
Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke
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June 2015 |
SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation
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December 2011 |
In defense of cell volume?
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November 1993 |
Functionally Linked Hydration Changes in Escherichia coli Aspartate Transcarbamylase and Its Catalytic Subunit †
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August 1997 |
Discovery and Characterization of Allosteric WNK Kinase Inhibitors
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October 2016 |
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
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August 2007 |
WNK Kinase Signaling in Ion Homeostasis and Human Disease
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February 2017 |
Protein hydration in solution: Experimental observation by x-ray and neutron scattering
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March 1998 |
Signaling Mechanisms of HAMP Domains in Chemoreceptors and Sensor Kinases
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October 2010 |
Dietary Salt Intake Regulates WNK3–SPAK–NKCC1 Phosphorylation Cascade in Mouse Aorta Through Angiotensin II
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November 2013 |
WNK1 Regulates Vasoconstriction and Blood Pressure Response to α 1 -Adrenergic Stimulation in Mice
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September 2011 |
The role of conserved water molecules in the catalytic domain of protein kinases
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August 2009 |
Mitogen-activated protein kinases as key players in osmotic stress signaling
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September 2016 |
Analysis of non-ideal behavior in concentrated hemoglobin solutions
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May 1977 |
A Phosphorylated Intermediate in the Activation of WNK Kinases
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April 2020 |
Human Hypertension Caused by Mutations in WNK Kinases
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August 2001 |
Substrate and Docking Interactions in Serine/Threonine Protein Kinases
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November 2007 |
Evolutionarily conserved WNK and Ste20 kinases are essential for acute volume recovery and survival after hypertonic shrinkage in Caenorhabditis elegans
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September 2007 |
The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
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October 2008 |
The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation.
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December 1992 |
Osmostress Induces Autophosphorylation of Hog1 via a C-Terminal Regulatory Region That Is Conserved in p38α
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September 2012 |
Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology
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October 2019 |
Regulation of WNK1 by an Autoinhibitory Domain and Autophosphorylation
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October 2002 |
Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation
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May 2014 |
Probing protein hydration and conformational states in solution
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March 1997 |
Small-molecule WNK inhibition regulates cardiovascular and renal function
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September 2016 |
HAMP Domain Conformers That Propagate Opposite Signals in Bacterial Chemoreceptors
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February 2013 |
Coot model-building tools for molecular graphics
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November 2004 |
From crystal to structure with CCP4
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March 2011 |
Robust Prediction of the MASCOT Score for an Improved Quality Assessment in Mass Spectrometric Proteomics
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September 2008 |
Osmosensing by Bacteria
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October 2006 |
WNK3 modulates transport of Cl- in and out of cells: Implications for control of cell volume and neuronal excitability
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November 2005 |
[Cl-]i-dependent Phosphorylation of the Na-K-Cl Cotransport Protein of Dog Tracheal Epithelial Cells
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December 1995 |
Amino acid composition and protein dimension
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December 2008 |
Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs
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February 2007 |
NKCC1 Chloride Importer Antagonists Attenuate Many Neurological and Psychiatric Disorders
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September 2017 |
Mechanism of Mitogen-activated Protein Kinase Phosphatase-3 Activation by ERK2
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December 1999 |
Sodium-Potassium-Chloride Cotransport
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January 2000 |
Crystal Structure of the Kinase Domain of WNK1, a Kinase that Causes a Hereditary Form of Hypertension
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July 2004 |
Roll: a new algorithm for the detection of protein pockets and cavities with a rolling probe sphere
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October 2009 |
OSR1 regulates a subset of inward rectifier potassium channels via a binding motif variant
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March 2018 |
The inner membrane histidine kinase EnvZ senses osmolality via helix-coil transitions in the cytoplasm: The mechanism of EnvZ osmosensing
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April 2012 |
Water-mediated conformational preselection mechanism in substrate binding cooperativity to protein kinase A
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March 2018 |