Using Nucleic Acid Microarrays To Perform Molecular Epidemiology and Detect Novel -Lactamases: a Snapshot of Extended-Spectrum -Lactamases throughout the World
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February 2012 |
MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes
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July 2004 |
Outbreak of Klebsiella pneumoniae Producing a New Carbapenem-Hydrolyzing Class A β-Lactamase, KPC-3, in a New York Medical Center
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December 2004 |
Atomic Resolution Structures of CTX-M β-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability
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April 2005 |
The Kinetics of the α-Chymotrypsin-Catalyzed Hydrolysis of p-Nitrophenyl Acetate *
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November 1962 |
Biochemical Characterization of SFC-1, a Class A Carbapenem-Hydrolyzing β-Lactamase
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September 2007 |
Overview of the CCP 4 suite and current developments
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March 2011 |
Carbapenems and SHV-1 β-Lactamase Form Different Acyl-Enzyme Populations in Crystals and Solution †
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November 2008 |
Facilitation of the .DELTA.2 .fwdarw. .DELTA.1 pyrroline tautomerization of carbapenem antibiotics by the highly conserved arginine-244 of class A .beta.-lactamases during the course of turnover
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February 1992 |
Single-turnover and steady-state kinetics of hydrolysis of cephalosporins by β-lactamase I from Bacillus cereus
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October 1985 |
The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme.
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March 1996 |
Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum β-Lactamases
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December 2014 |
The ficin-catalysed hydrolysis of p -nitrophenyl hippurate. Detailed kinetics including the measurement of the apparent dissociation constant for the enzyme-substrate complex
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August 1969 |
Structural and Biochemical Evidence That a TEM-1 β-Lactamase N170G Active Site Mutant Acts via Substrate-assisted Catalysis
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October 2009 |
Amino Acid Sequence Requirements at Residues 69 and 238 for the SME-1 β-Lactamase To Confer Resistance to β-Lactam Antibiotics
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March 2003 |
Three Decades of the Class A β-Lactamase Acyl-Enzyme
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October 2009 |
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
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October 2019 |
Natural Variants of the KPC-2 Carbapenemase have Evolved Increased Catalytic Efficiency for Ceftazidime Hydrolysis at the Cost of Enzyme Stability
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June 2015 |
How good are my data and what is the resolution?
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June 2013 |
Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of Klebsiella pneumoniae
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April 2001 |
Conformational Intermediate That Controls KPC-2 Catalysis and Beta-Lactam Drug Resistance
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February 2018 |
The Structure of <latex>$\beta$</latex>-Lactamases
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May 1980 |
Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases
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February 2018 |
Structural Basis for Substrate Specificity and Carbapenemase Activity of OXA-48 Class D β-Lactamase
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December 2019 |
Cloning and sequence analysis of the gene for a carbapenem-hydrolyzing class A beta-lactamase, Sme-1, from Serratia marcescens S6.
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June 1994 |
Amino Acid Residues That Contribute to Substrate Specificity of Class A β-Lactamase SME-1
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August 2005 |
Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli
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November 1983 |
iMOSFLM : a new graphical interface for diffraction-image processing with MOSFLM
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March 2011 |
Crystal Structure of KPC-2: Insights into Carbapenemase Activity in Class A β-Lactamases † , ‡
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May 2007 |
Molecular Characterization of a Carbapenem-Hydrolyzing Class A β-Lactamase, SFC-1, from Serratia fonticola UTAD54
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June 2004 |
The analysis of enzyme progress curves by numerical differentiation, including competitive product inhibition and enzyme reactivation
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August 1987 |
Contributions of Aspartate 49 and Phenylalanine 142 Residues of a Tight Binding Inhibitory Protein of β-Lactamases
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January 1999 |
Inhibition of the NMC-A β-Lactamase by a Penicillanic Acid Derivative and the Structural Bases for the Increase in Substrate Profile of This Antibiotic Resistance Enzyme
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September 1998 |
Ground State Destabilization by Anionic Nucleophiles Contributes to the Activity of Phosphoryl Transfer Enzymes
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July 2013 |
Structural Basis for Clinical Longevity of Carbapenem Antibiotics in the Face of Challenge by the Common Class A β-Lactamases from the Antibiotic-Resistant Bacteria
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September 1998 |
KPC-9, a Novel Carbapenemase from Clinical Specimens in Israel
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September 2012 |
An Ultrahigh Resolution Structure of TEM-1 β-Lactamase Suggests a Role for Glu166 as the General Base in Acylation
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May 2002 |
Carbapenems, a new class of beta-lactam antibiotics
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June 1985 |
ExPASy: SIB bioinformatics resource portal
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May 2012 |
Metallo-β-lactamase structure and function: Metallo-β-lactamase structure and function
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November 2012 |
Molecular Basis of Substrate Recognition and Product Release by the Klebsiella pneumoniae Carbapenemase (KPC-2)
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April 2017 |
Features and development of Coot
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March 2010 |
Inhibition of Class A β-Lactamases by Carbapenems: Crystallographic Observation of Two Conformations of Meropenem in SHV-1
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September 2008 |
Structural Insights into Substrate Recognition and Product Expulsion in CTX-M Enzymes
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July 2010 |
Mechanism of turnover of imipenem by the TEM .beta.-lactamase revisited
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July 1995 |
Sparing carbapenem usage
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June 2017 |
Molecular structure of the acyl-enzyme intermediate in β-lactam hydrolysis at 1.7 Å resolution
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October 1992 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation
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June 2017 |
Antibiotic Resistance and Substrate Profiles of the Class A Carbapenemase KPC-6
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August 2012 |
Detection of KPC in Acinetobacter spp. in Puerto Rico
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December 2009 |
Carbapenems: Past, Present, and Future
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August 2011 |
The Basis for Carbapenem Hydrolysis by Class A β-Lactamases: A Combined Investigation using Crystallography and Simulations
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October 2012 |
Kinetic and Structural Requirements for Carbapenemase Activity in GES-Type β-Lactamases
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December 2014 |
Iterative-build OMIT maps: map improvement by iterative model building and refinement without model bias
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April 2008 |
Inhibition of the RTEM .beta.-lactamase from Escherichia coli. Interaction of the enzyme with derivatives of olivanic acid
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June 1982 |
Imipenem as substrate and inhibitor of β-lactamases
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July 1988 |
Mechanistic Basis for the Emergence of Catalytic Competence against Carbapenem Antibiotics by the GES Family of β-Lactamases
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October 2009 |
Penicillin-binding proteins: evergreen drug targets
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October 2014 |
Phaser crystallographic software
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July 2007 |
Biochemical and Structural Characterization of Mycobacterium tuberculosis β-Lactamase with the Carbapenems Ertapenem and Doripenem
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May 2010 |