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Title: Draft Genome Sequence of a Mucoid Isolate of Pseudomonas aeruginosa Strain C7447m from a Patient with Cystic Fibrosis

Journal Article · · Genome Announcements
 [1];  [2];  [3];  [4]
  1. Marshall Univ., Huntington, WV (United States). Joan C. Edwards School of Medicine. Dept. of Biochemistry and Microbiology
  2. Marshall Univ., Huntington, WV (United States). Joan C. Edwards School of Medicine. Dept. of Biochemistry and Microbiology
  3. Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Genome Science Group
  4. Marshall Univ., Huntington, WV (United States). Joan C. Edwards School of Medicine. Dept. of Biochemistry and Microbiology; Marshall Univ., Huntington, WV (United States). Joan C. Edwards School of Medicine. Dept. of Pediatrics; Progenesis Technologies, LLC, Huntington, WV (United States)
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Alginate overproduction by Pseudomonas aeruginosa, or mucoidy, plays an important role in the pathogenesis of chronic lung infections in cystic fibrosis (CF) patients. Here we report the draft genome sequence of a clinical isolate of mucoid P. aeruginosa strain C7447m from a CF patient with chronic lung infection.

Research Organization:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science Division
OSTI ID:
1629341
Journal Information:
Genome Announcements, Vol. 1, Issue 5; ISSN 2169-8287
Publisher:
American Society for MicrobiologyCopyright Statement
Country of Publication:
United States
Language:
English

References (6)

ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa journal July 2008
Truncation of type IV pilin induces mucoidy in P seudomonas aeruginosa strain PAO579 journal March 2013
Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia journal September 1996
The Pseudomonas aeruginosa Sensor Kinase KinB Negatively Controls Alginate Production through AlgW-Dependent MucA Proteolysis journal January 2009
The Exopolysaccharide Alginate Protects Pseudomonas aeruginosa Biofilm Bacteria from IFN-γ-Mediated Macrophage Killing journal November 2005
Bacterial biosynthesis of alginates journal March 2010

Cited By (1)

Ribosomally encoded antibacterial proteins and peptides from Pseudomonas journal July 2014

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59 BASIC BIOLOGICAL SCIENCES