Multifunctional skin-like electronics for quantitative, clinical monitoring of cutaneous wound healing

Hattori, Yoshiaki; Falgout, Leo; Lee, Woosik; Jung, Sung -Young; Poon, Emily; Lee, Jung Woo; Na, Ilyoun; Geisler, Amelia; Sadhwani, Divya; Zhang, Yihui; Su, Yewang; Wang, Xiaoqi; Liu, Zhuangjian; Xia, Jing; Cheng, Huanyu; Webb, R. Chad; Bonifas, Andrew P.; Won, Philip; Jeong, Jae -Woong; Jang, Kyung -In; Song, Young Min; Nardone, Beatrice; Nodzenski, Michael; Fan, Jonathan A.; Huang, Yonggang; West, Dennis P.; Paller, Amy S.; Alam, Murad; Yeo, Woon -Hong; Rogers, John A.

doi:10.1002/adhm.201400073

Title: Multifunctional skin-like electronics for quantitative, clinical monitoring of cutaneous wound healing

Journal Article · Wed Mar 26 00:00:00 EDT 2014 · Advanced Healthcare Materials

DOI:https://doi.org/10.1002/adhm.201400073· OSTI ID:1342721

Hattori, Yoshiaki ^[1]; Falgout, Leo ^[1]; Lee, Woosik ^[1]; Jung, Sung -Young ^[2]; Poon, Emily ^[3]; Lee, Jung Woo ^[1]; Na, Ilyoun ^[2]; Geisler, Amelia ^[3]; Sadhwani, Divya ^[3]; Zhang, Yihui ^[4]; Su, Yewang ^[4]; Wang, Xiaoqi ^[3]; Liu, Zhuangjian ^[5]; Xia, Jing ^[4]; Cheng, Huanyu ^[6]; Webb, R. Chad ^[1]; Bonifas, Andrew P. ^[1]; Won, Philip ^[1]; Jeong, Jae -Woong ^[1]; Jang, Kyung -In ^[1] more »

Univ. of Illinois at Urbana-Champaign, Urbana, IL (United States)
Pohang Univ. of Science and Technology, Pohang (Republic of Korea)
Northwestern Univ., Chicago, IL (United States)
Northwestern Univ., Evanston, IL (United States); Center for Mechanics and Materials, Beijing (China)
Institute of High Performance Computing, Connexis (Singapore)
Northwestern Univ., Evanston, IL (United States)
Pusan National Univ., Busan (Republic of Korea)
Virginia Commonwealth Univ., Richmond, VA (United States)

Non-invasive, biomedical devices have the potential to provide important, quantitative data for the assessment of skin diseases and wound healing. Traditional methods either rely on qualitative visual and tactile judgments of a professional and/or data obtained using instrumentation with forms that do not readily allow intimate integration with sensitive skin near a wound site. In this paper, an electronic sensor platform that can softly and reversibly laminate perilesionally at wounds to provide highly accurate, quantitative data of relevance to the management of surgical wound healing is reported. Clinical studies on patients using thermal sensors and actuators in fractal layouts provide precise time-dependent mapping of temperature and thermal conductivity of the skin near the wounds. Analytical and simulation results establish the fundamentals of the sensing modalities, the mechanics of the system, and strategies for optimized design. The use of this type of “epidermal” electronics system in a realistic clinical setting with human subjects establishes a set of practical procedures in disinfection, reuse, and protocols for quantitative measurement. Finally, the results have the potential to address important unmet needs in chronic wound management.

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Research Organization:: Univ. of Illinois at Urbana-Champaign, IL (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: FG02-07ER46471; FG02-07ER46453

OSTI ID:: 1342721

Journal Information:: Advanced Healthcare Materials, Vol. 3, Issue 10; ISSN 2192-2640

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 200 works

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References (33)

Sensors and imaging for wound healing: A review Dargaville, Tim R.; Farrugia, Brooke L.; Broadbent, James A. Biosensors and Bioelectronics, Vol. 41 https://doi.org/10.1016/j.bios.2012.09.029	journal	March 2013
Orchestrating Wound Healing: Assessing and Preparing the Wound Bed Hess, Cathy Thomas; Kirsner, Robert S. Advances in Skin & Wound Care, Vol. 16, Issue 5 https://doi.org/10.1097/00129334-200309000-00015	journal	January 2003
Vibrational spectroscopy: a tool being developed for the noninvasive monitoring of wound healing Crane, Nicole J.; Elster, Eric A. Journal of Biomedical Optics, Vol. 17, Issue 1 https://doi.org/10.1117/1.JBO.17.1.010902	journal	January 2012
Factors Affecting Wound Healing Guo, S.; DiPietro, L. A. Journal of Dental Research, Vol. 89, Issue 3 https://doi.org/10.1177/0022034509359125	journal	February 2010
Real-time monitoring of moisture levels in wound dressings in vitro: An experimental study McColl, David; Cartlidge, Brian; Connolly, Patricia International Journal of Surgery, Vol. 5, Issue 5 https://doi.org/10.1016/j.ijsu.2007.02.008	journal	October 2007
Epidermal Electronics Kim, D.-H.; Lu, N.; Ma, R. Science, Vol. 333, Issue 6044, p. 838-843 https://doi.org/10.1126/science.1206157	journal	August 2011
Materials and Optimized Designs for Human-Machine Interfaces Via Epidermal Electronics Jeong, Jae-Woong; Yeo, Woon-Hong; Akhtar, Aadeel Advanced Materials, Vol. 25, Issue 47 https://doi.org/10.1002/adma.201301921	journal	September 2013
Multifunctional Epidermal Electronics Printed Directly Onto the Skin Yeo, Woon-Hong; Kim, Yun-Soung; Lee, Jongwoo Advanced Materials, Vol. 25, Issue 20, p. 2773-2778 https://doi.org/10.1002/adma.201204426	journal	February 2013
Occlusive dressings and wound healing Helfman, Todd; Ovington, Liza; Falanga, Vincent Clinics in Dermatology, Vol. 12, Issue 1 https://doi.org/10.1016/0738-081X(94)90262-3	journal	January 1994
Cutaneous Wound Healing Singer, Adam J.; Clark, Richard A. F. New England Journal of Medicine, Vol. 341, Issue 10 https://doi.org/10.1056/NEJM199909023411006	journal	September 1999
Epidermal Impedance Sensing Sheets for Precision Hydration Assessment and Spatial Mapping IEEE Transactions on Biomedical Engineering, Vol. 60, Issue 10 https://doi.org/10.1109/TBME.2013.2264879	journal	October 2013
Epidermal Differential Impedance Sensor for Conformal Skin Hydration Monitoring Huang, Xian; Yeo, Woon-Hong; Liu, Yuhao Biointerphases, Vol. 7, Issue 1, Article No. 52 https://doi.org/10.1007/s13758-012-0052-8	journal	December 2012
Erratum: Ultrathin conformal devices for precise and continuous thermal characterization of human skin Webb, R. Chad; Bonifas, Andrew P.; Behnaz, Alex Nature Materials, Vol. 12, Issue 11 https://doi.org/10.1038/nmat3779	journal	October 2013
Fractal design concepts for stretchable electronics Fan, Jonathan A.; Yeo, Woon-Hong; Su, Yewang Nature Communications, Vol. 5, Article No. 3266 (2014) https://doi.org/10.1038/ncomms4266	journal	February 2014
Digital cameras with designs inspired by the arthropod eye Song, Young Min; Xie, Yizhu; Malyarchuk, Viktor Nature, Vol. 497, Issue 7447 https://doi.org/10.1038/nature12083	journal	May 2013
Buckling in serpentine microstructures and applications in elastomer-supported ultra-stretchable electronics with high areal coverage Zhang, Yihui; Xu, Sheng; Fu, Haoran Soft Matter, Vol. 9, Issue 33 https://doi.org/10.1039/c3sm51360b	journal	January 2013
Thermal conductivity measurement from 30 to 750 K: the 3ω method Cahill, David G. Review of Scientific Instruments, Vol. 61, Issue 2 https://doi.org/10.1063/1.1141498	journal	February 1990
Absolute measurements of the thermal conductivity of mixtures of alcohols with water Assael, M. J.; Charitidou, E.; Wakeham, W. A. International Journal of Thermophysics, Vol. 10, Issue 4 https://doi.org/10.1007/BF00514476	journal	July 1989
Real-time thermal characterization of 12nl fluid samples in a microchannel Choi, Sun Rock; Kim, Dongsik Review of Scientific Instruments, Vol. 79, Issue 6 https://doi.org/10.1063/1.2937180	journal	June 2008
Thermal conductivity of solid deuterium by the 3ω method Gram, R. Q.; She, A.; Craxton, R. S. Journal of Applied Physics, Vol. 112, Issue 3 https://doi.org/10.1063/1.4739285	journal	August 2012
Thermal tumour ablation: Devices, clinical applications and future directions Haemmerich, D.; Laeseke, P. F. International Journal of Hyperthermia, Vol. 21, Issue 8 https://doi.org/10.1080/02656730500226423	journal	December 2005
Thin, Flexible Sensors and Actuators as ‘Instrumented’ Surgical Sutures for Targeted Wound Monitoring and Therapy Kim, Dae-Hyeong; Wang, Shuodao; Keum, Hohyun Small, Vol. 8, Issue 21, p. 3263-3268 https://doi.org/10.1002/smll.201200933	journal	August 2012
Construction of a Conformal Water Bolus Vest Applicator for Hyperthermia Treatment of Superficial Skin Cancer Juang, T.; Neuman, D.; Schlorff, J. The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society https://doi.org/10.1109/IEMBS.2004.1403973	conference	January 2004
Antiseptics and Disinfectants: Activity, Action, and Resistance McDonnell, Gerald; Russell, A. Denver Clinical Microbiology Reviews, Vol. 12, Issue 1 https://doi.org/10.1128/CMR.12.1.147	journal	January 1999
Dry solution to a sticky problem Karp, Jeffrey M.; Langer, Robert Nature, Vol. 477, Issue 7362 https://doi.org/10.1038/477042a	journal	August 2011
Rational Design and Enhanced Biocompatibility of a Dry Adhesive Medical Skin Patch Kwak, Moon Kyu; Jeong, Hoon-Eui; Suh, Kahp Y. Advanced Materials, Vol. 23, Issue 34, p. 3949-3953 https://doi.org/10.1002/adma.201101694	journal	July 2011
Towards the Next Level of Bioinspired Dry Adhesives: New Designs and Applications Kwak, Moon Kyu; Pang, Changhyun; Jeong, Hoon-Eui Advanced Functional Materials, Vol. 21, Issue 19 https://doi.org/10.1002/adfm.201100982	journal	September 2011
Quick-release medical tape Laulicht, B.; Langer, R.; Karp, J. M. Proceedings of the National Academy of Sciences, Vol. 109, Issue 46 https://doi.org/10.1073/pnas.1216071109	journal	October 2012
Neurotoxic amyloid beta oligomeric assemblies recreated in microfluidic platform with interstitial level of slow flow Choi, Yoon Jung; Chae, Sukyung; Kim, Jeong Hun Scientific Reports, Vol. 3, Issue 1 https://doi.org/10.1038/srep01921	journal	May 2013
CNT/PDMS Composite Flexible Dry Electrodesfor Long-Term ECG Monitoring Jung, Ha-Chul; Moon, Jin-Hee; Baek, Dong-Hyun IEEE Transactions on Biomedical Engineering, Vol. 59, Issue 5, p. 1472-1479 https://doi.org/10.1109/TBME.2012.2190288	journal	May 2012
A capacitive, biocompatible and adhesive electrode for long-term and cap-free monitoring of EEG signals Lee, Seung Min; Kim, Jeong Hun; Byeon, Hang Jin Journal of Neural Engineering, Vol. 10, Issue 3 https://doi.org/10.1088/1741-2560/10/3/036006	journal	April 2013
Wound healing monitoring using near infrared fluorescent fibrinogen Pan, Chia-Pin; Shi, Yihui; Amin, Khalid Biomedical Optics Express, Vol. 1, Issue 1 https://doi.org/10.1364/BOE.1.000285	journal	January 2010
A dressing history Queen, Douglas; Orsted, Heather; Sanada, Hiromi International Wound Journal, Vol. 1, Issue 1 https://doi.org/10.1111/j.1742-4801.2004.0009.x	journal	April 2004

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