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Title: Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate

Patent ·
OSTI ID:1014558
 [1];  [2];  [3];  [4];  [5];  [6];  [2];  [7]
  1. Kennett Square, PA
  2. Lakewood, CO
  3. Centennial, CO
  4. Newark, DE
  5. Havertown, PA
  6. West Chester, PA
  7. New Hope, PA

Through screening of a Zymomonas mutant library the himA gene was found to be involved in the inhibitory effect of acetate on Zymomonas performance. Xylose-utilizing Zymomonas further engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in medium comprising xylose and acetate.

Research Organization:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC36-08GO28308
Assignee:
E.I. du Pont de Nemours and Company (Wilmington, DE); Alliance for Sustainable Energy LLC (Wilmington, DE)
Patent Number(s):
7,803,623
Application Number:
US Patent Application 12/261,166
OSTI ID:
1014558
Country of Publication:
United States
Language:
English

References (21)

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Performance of a newly developed integrant of Zymomonas mobilis for ethanol production on corn stover hydrolysate journal February 2004
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