Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer

Chen, Yu; Leach, Franklin E.; Kaiser, Nathan K.; Dang, Xibei; Ibrahim, Yehia M.; Norheim, Randolph V.; Anderson, Gordon A.; Smith, Richard D.; Marshall, Alan G.

doi:10.1002/jms.3523

Title: Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer

Journal Article · Mon Jan 19 00:00:00 EST 2015 · Journal of Mass Spectrometry

DOI:https://doi.org/10.1002/jms.3523· OSTI ID:1188871

Chen, Yu ^[1]; Leach, Franklin E. ^[2]; Kaiser, Nathan K. ^[1]; Dang, Xibei ^[3]; Ibrahim, Yehia M. ^[2]; Norheim, Randolph V. ^[2]; Anderson, Gordon A. ^[2]; Smith, Richard D. ^[2]; Marshall, Alan G. ^[4]

Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab. (MagLab), Ion Cyclotron Resonance Program
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry
Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab. (MagLab), Ion Cyclotron Resonance Program; Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry

Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry provides unparalleled mass accuracy and resolving power.[1],[2] With electrospray ionization (ESI), ions are typically transferred into the mass spectrometer through a skimmer, which serves as a conductance-limiting orifice. However, the skimmer allows only a small fraction of incoming ions to enter the mass spectrometer. An ion funnel, originally developed by Smith and coworkers at Pacific Northwest National Laboratory (PNNL)[3-5] provides much more efficient ion focusing and transfer. The large entrance aperture of the ion funnel allows almost all ions emanating from a heated capillary to be efficiently captured and transferred, resulting in nearly lossless transmission.

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Research Organization:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States). Environmental Molecular Sciences Laboratory (EMSL)

Sponsoring Organization:: USDOE; National Science Foundation (NSF)

Grant/Contract Number:: AC05-76RL01830; CHE-1019193; DMR-11-57490; P41 GM103493

OSTI ID:: 1188871

Report Number(s):: PNNL-SA-104452; 48135; 47418; KP1601010

Journal Information:: Journal of Mass Spectrometry, Vol. 50, Issue 1; ISSN 1076-5174

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

Citation Metrics:

Cited by: 12 works

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References (23)

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Title: Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer

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