Absorbed dose to the fetus during bone scintigraphy

Journal Article · Fri Jul 01 00:00:00 EDT 1988 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.168.1.3380967· OSTI ID:6859128

Hedrick, W R; DiSimone, R N; Wolf, B H; Langer, A

The authors observed the uptake of radiopharmaceutical and calculated absorbed dose in fetuses of two patients who underwent bone scintigraphy with technetium-99m methylene diphosphonate. Dose estimates per administered activity were 17 mrad/mCi (4.6 microGy/MBq) for an 8-week-old fetus and 9.7 mrad/mCi (2.6 microGy/MBq) for an 18-week-old fetus. Neither fetus demonstrated radionuclide uptake above maternal background levels. The uterine activity showed rapid clearance, with an effective half-life of 12 minutes after reaching a maximum within 1 minute after injection. Major contribution to fetal dose comes from the presence of the radionuclide in the maternal bladder. The authors conclude that bone scintigraphy performed unknowingly in pregnant individuals presents negligible increased risk to the fetus.

• Research Organization: Aultman Hospital, Canton, OH (USA)
• OSTI ID: 6859128
• Journal Information: Radiology; (United States), Vol. 168:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
FETUSES
RADIATION DOSES
SKELETON
SCINTISCANNING
BIOLOGICAL HALF-LIFE
ISOMERIC NUCLEI
PATIENTS
PREGNANCY
RISK ASSESSMENT
TECHNETIUM 99
UTERUS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DOSES
FEMALE GENITALS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics