Immune resistance of semisyngeneic F1 hybrid mice to lymphoma grafts differs from natural hybrid resistance in its genetic pattern
Journal Article
·
· Cell. Immunol.; (United States)
Resistance of semisyngeneic F1 hybrid mice immunized three times with irradiated tumor cells was compared to the genetic pattern of natural hybrid resistance to challenge with live tumor cells. Syngeneic mice responded equally well to immunization with all five hemopoietic tumor lines tested as the naturally much more highly resistant F1 hybrids. Natural hybrid resistance was found to be severely reduced by sublethal irradiation with 4 Gy, in contrast to hybrid resistance to parental bone marrow.
- Research Organization:
- Karolinska Inst., Stockholm, Sweden
- OSTI ID:
- 6353282
- Journal Information:
- Cell. Immunol.; (United States), Vol. 86:2
- Country of Publication:
- United States
- Language:
- English
Similar Records
Natural resistance of lethally irradiated F1 hybrid mice to parental marrow grafts is a function of H-2/Hh-restricted effectors
Induction of immune resistance against L1210 lymphatic leukemia in mice after chemoradiotherapy of the leukemia and reconstitution with bone marrow purged from the leukemia with mafosfamide
In vivo natural antitumor resistance against murine EL-4 lymphoma cells in lethally irradiated syngeneic C57Bl/6 mice
Journal Article
·
Sun Apr 01 00:00:00 EST 1984
· J. Exp. Med.; (United States)
·
OSTI ID:6353282
Induction of immune resistance against L1210 lymphatic leukemia in mice after chemoradiotherapy of the leukemia and reconstitution with bone marrow purged from the leukemia with mafosfamide
Journal Article
·
Sat Oct 01 00:00:00 EDT 1988
· Exp. Hematol.; (United States)
·
OSTI ID:6353282
In vivo natural antitumor resistance against murine EL-4 lymphoma cells in lethally irradiated syngeneic C57Bl/6 mice
Journal Article
·
Sat Aug 01 00:00:00 EDT 1987
· Cell. Immunol.; (United States)
·
OSTI ID:6353282
+2 more
Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
MICE
IMMUNITY
SUBLETHAL IRRADIATION
IMMUNOSUPPRESSION
TUMOR CELLS
IMMUNE REACTIONS
BONE MARROW
GRAFTS
LYMPHOMAS
ANIMAL CELLS
ANIMAL TISSUES
ANIMALS
BODY
DISEASES
HEMATOPOIETIC SYSTEM
IRRADIATION
MAMMALS
NEOPLASMS
ORGANS
RODENTS
TISSUES
TRANSPLANTS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals
551000 - Physiological Systems
59 BASIC BIOLOGICAL SCIENCES
MICE
IMMUNITY
SUBLETHAL IRRADIATION
IMMUNOSUPPRESSION
TUMOR CELLS
IMMUNE REACTIONS
BONE MARROW
GRAFTS
LYMPHOMAS
ANIMAL CELLS
ANIMAL TISSUES
ANIMALS
BODY
DISEASES
HEMATOPOIETIC SYSTEM
IRRADIATION
MAMMALS
NEOPLASMS
ORGANS
RODENTS
TISSUES
TRANSPLANTS
VERTEBRATES
560152* - Radiation Effects on Animals- Animals
551000 - Physiological Systems