Validation of thermal techniques for measurement of pelvic organ blood flows in the nonpregnant sheep: comparison with transit-time ultrasonic and microsphere measurements of blood flow

Journal Article · Tue Mar 01 00:00:00 EST 1988 · Am. J. Obstet. Gynecol.; (United States)

DOI:https://doi.org/10.1016/0002-9378(88)90048-8· OSTI ID:5234153

Randall, N J; Beard, R W; Sutherland, I A; Figueroa, J P; Drost, C J; Nathanielsz, P W

Data obtained from a thermal system capable of measuring changes in organ temperature as well as tissue thermal clearance in the uterus and vagina have been compared with blood flow measured continuously with a transit-time ultrasound volume-flow sensor placed around the common internal iliac artery and intermittently with radioactive microspheres in the chronically instrumented nonpregnant sheep. Temperature changes in both the uterus and the vagina correlated well with blood flow changes measured by both techniques after intravenous administration of estradiol or norepinephrine. Thermal clearance did not correlate well with blood flow in the vagina or uterus. These methods may have value in the investigation of blood flow patterns in various clinical situations such as the pelvic pain syndrome and early pregnancy.

• Research Organization: St. Mary's Hospital Medical School, London (England)
• OSTI ID: 5234153
• Journal Information: Am. J. Obstet. Gynecol.; (United States), Vol. 158
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
BLOOD FLOW
MEASURING METHODS
UTERUS
BODY TEMPERATURE
ESTRADIOL
FLOWMETERS
INTRAVENOUS INJECTION
MICROSPHERES
NORADRENALINE
PELVIS
RADIOISOTOPES
SHEEP
TRACER TECHNIQUES
VALIDATION
ADRENAL HORMONES
ANIMALS
AUTONOMIC NERVOUS SYSTEM AGENTS
BODY
BODY AREAS
CARDIOTONICS
CARDIOVASCULAR AGENTS
DOMESTIC ANIMALS
DRUGS
ESTRANES
ESTROGENS
FEMALE GENITALS
HORMONES
HYDROXY COMPOUNDS
INJECTION
INTAKE
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MEASURING INSTRUMENTS
METERS
NEUROREGULATORS
ORGANIC COMPOUNDS
ORGANS
RUMINANTS
STEROID HORMONES
STEROIDS
SYMPATHOMIMETICS
TESTING
VERTEBRATES
551001* - Physiological Systems- Tracer Techniques