Autism and genetics: Clinical approach and association study with two markers of HRAS gene
Journal Article
·
· American Journal of Medical Genetics
- Laboratoire de Biochimie Medicale, Tours (France); and others
Twin studies and familial aggregation studies indicate that genetic factors could play a role in infantile autism. In an earlier study, we identified a possible positive association between autism and a c-Harvey-ras (HRAS) oncogene marker at the 3{prime} end of the coding region. In an attempt to confirm this finding, we studied a larger population, well-characterized clinically and genetically. We report a positive association between autism and two HRAS markers, the 3{prime} marker used in the initial study and an additional marker in exon 1. 46 refs., 1 fig., 2 tabs.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 426172
- Journal Information:
- American Journal of Medical Genetics, Vol. 60, Issue 4; Other Information: PBD: 14 Aug 1995
- Country of Publication:
- United States
- Language:
- English
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