Solid-phase extraction microfluidic devices for matrix removal in trace element assay of actinide materials
Abstract
Advances in sample nebulization and injection technology have significantly reduced the volume of solution required for trace impurity analysis in plutonium and uranium materials. Correspondingly, we have designed and tested a novel chip-based microfluidic platform, containing a 100-µL or 20-µL solid-phase microextraction column, packed by centrifugation, which supports nuclear material mass and solution volume reductions of 90% or more compared to standard methods. Quantitative recovery of 28 trace elements in uranium was demonstrated using a UTEVA chromatographic resin column, and trace element recovery from thorium (a surrogate for plutonium) was similarly demonstrated using anion exchange resin AG MP-1. Of nine materials tested, compatibility of polyvinyl chloride (PVC), polypropylene (PP), and polytetrafluoroethylene (PTFE) chips with the strong nitric acid media was highest. Finally, the microcolumns can be incorporated into a variety of devices and systems, and can be loaded with other solid-phase resins for trace element assay in high-purity metals.
- Publication Date:
- Research Org.:
- Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE National Nuclear Security Administration (NNSA), Office of Defense Programs (DP)
- OSTI Identifier:
- 1343715
- Alternate Identifier(s):
- OSTI ID: 1416754
- Report Number(s):
- LA-UR-16-26781
Journal ID: ISSN 0039-9140
- Grant/Contract Number:
- AC52-06NA25396
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Talanta
- Additional Journal Information:
- Journal Volume: 167; Journal Issue: C; Journal ID: ISSN 0039-9140
- Publisher:
- Elsevier
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS; uranium, plutonium, quality, nuclear forensics, anion exchange, chromatography, spectroscopy, microchemistry; microfluidic device; trace impurity; plutonium; uranium; nuclear forensics
Citation Formats
Gao, Jun, Manard, Benjamin Thomas, Castro, Alonso, Montoya, Dennis Patrick, Xu, Ning, and Chamberlin, Rebecca M. Solid-phase extraction microfluidic devices for matrix removal in trace element assay of actinide materials. United States: N. p., 2017.
Web. doi:10.1016/j.talanta.2017.01.080.
Gao, Jun, Manard, Benjamin Thomas, Castro, Alonso, Montoya, Dennis Patrick, Xu, Ning, & Chamberlin, Rebecca M. Solid-phase extraction microfluidic devices for matrix removal in trace element assay of actinide materials. United States. https://doi.org/10.1016/j.talanta.2017.01.080
Gao, Jun, Manard, Benjamin Thomas, Castro, Alonso, Montoya, Dennis Patrick, Xu, Ning, and Chamberlin, Rebecca M. Thu .
"Solid-phase extraction microfluidic devices for matrix removal in trace element assay of actinide materials". United States. https://doi.org/10.1016/j.talanta.2017.01.080. https://www.osti.gov/servlets/purl/1343715.
@article{osti_1343715,
title = {Solid-phase extraction microfluidic devices for matrix removal in trace element assay of actinide materials},
author = {Gao, Jun and Manard, Benjamin Thomas and Castro, Alonso and Montoya, Dennis Patrick and Xu, Ning and Chamberlin, Rebecca M.},
abstractNote = {Advances in sample nebulization and injection technology have significantly reduced the volume of solution required for trace impurity analysis in plutonium and uranium materials. Correspondingly, we have designed and tested a novel chip-based microfluidic platform, containing a 100-µL or 20-µL solid-phase microextraction column, packed by centrifugation, which supports nuclear material mass and solution volume reductions of 90% or more compared to standard methods. Quantitative recovery of 28 trace elements in uranium was demonstrated using a UTEVA chromatographic resin column, and trace element recovery from thorium (a surrogate for plutonium) was similarly demonstrated using anion exchange resin AG MP-1. Of nine materials tested, compatibility of polyvinyl chloride (PVC), polypropylene (PP), and polytetrafluoroethylene (PTFE) chips with the strong nitric acid media was highest. Finally, the microcolumns can be incorporated into a variety of devices and systems, and can be loaded with other solid-phase resins for trace element assay in high-purity metals.},
doi = {10.1016/j.talanta.2017.01.080},
journal = {Talanta},
number = C,
volume = 167,
place = {United States},
year = {Thu Feb 02 00:00:00 EST 2017},
month = {Thu Feb 02 00:00:00 EST 2017}
}
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