Miktoarm Star Polymers: Synthesis and Applications

Liu, Min; Blankenship, Jacob R.; Levi, Adam E.; Fu, Qiang; Hudson, Zachary M.; Bates, Christopher M.

doi:10.1021/acs.chemmater.2c01220

Title: Miktoarm Star Polymers: Synthesis and Applications

Journal Article · 10 July 2022 · Chemistry of Materials

DOI: https://doi.org/10.1021/acs.chemmater.2c01220 · OSTI ID:1971663

^[1]; Blankenship, Jacob R. ^[2]; Levi, Adam E. ^[2];

^[3];

^[4];

^[2]

Univ. of British Columbia, Vancouver, BC (Canada); UC Santa Barbara
Univ. of California, Santa Barbara, CA (United States)
Univ. of Technology Sydney, New South Wales (Australia)
Univ. of British Columbia, Vancouver, BC (Canada)

Polymers with precisely controlled structure and function are in high demand across a diverse array of applications spanning the life sciences and nanotechnology. One prototypical example is a class of branched block copolymers known as miktoarm stars (μ-stars), which contain two or more arm compositions connected at a common junction. Miktoarm stars have attracted considerable attention since their physical properties can be different from conventional linear block copolymers. This perspective highlights the latest developments and historical context in the field of miktoarm star polymers, including design strategies, synthetic techniques, and advanced characterization tools used to avoid common preparation pitfalls and tailor properties for emerging applications. Furthermore, our contemporary perspective on μ-star polymers is a resource for inspiring future research into this exciting class of materials at the intersection of chemistry, physics, and advanced technology.

View Accepted Manuscript (DOE)

Cite

Export

Save

Research Organization:: Univ. of California, Santa Barbara, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0019001

OSTI ID:: 1971663

Journal Information:: Chemistry of Materials, Journal Name: Chemistry of Materials Journal Issue: 14 Vol. 34; ISSN 0897-4756

Publisher:: American Chemical Society (ACS)Copyright Statement

Country of Publication:: United States

Language:: English

References (116)

Synthesis of miktoarm star (?-star) polymers Hadjichristidis, Nikos Journal of Polymer Science Part A: Polymer Chemistry, Vol. 37, Issue 7 https://doi.org/10.1002/(SICI)1099-0518(19990401)37:7<857::AID-POLA1>3.0.CO;2-P	journal	April 1999
Architectural Effects of Star‐Shaped “Structurally Nanoengineered Antimicrobial Peptide Polymers” (SNAPPs) on Their Biological Activity Shirbin, Steven J.; Insua, Ignacio; Holden, James A. Advanced Healthcare Materials, Vol. 7, Issue 21 https://doi.org/10.1002/adhm.201800627	journal	September 2018
Advanced Materials by Atom Transfer Radical Polymerization Matyjaszewski, Krzysztof Advanced Materials, Vol. 30, Issue 23 https://doi.org/10.1002/adma.201706441	journal	March 2018
Miktoarm Star Polymers with Environment‐Selective ROS/GSH Responsive Locations: From Modular Synthesis to Tuned Drug Release through Micellar Partial Corona Shedding and/or Core Disassembly Lotocki, Victor; Yazdani, Hossein; Zhang, Qiaochu Macromolecular Bioscience, Vol. 21, Issue 2 https://doi.org/10.1002/mabi.202000305	journal	November 2020
Brush-First Synthesis of Core-Photodegradable Miktoarm Star Polymers via ROMP: Towards Photoresponsive Self-Assemblies Burts, Alan O.; Gao, Angela X.; Johnson, Jeremiah A. Macromolecular Rapid Communications, Vol. 35, Issue 2 https://doi.org/10.1002/marc.201300618	journal	November 2013
An Arm-First Approach to Cleavable Mikto-Arm Star Polymers by RAFT Polymerization Wei, Xiaohu; Moad, Graeme; Muir, Benjamin W. Macromolecular Rapid Communications, Vol. 35, Issue 8 https://doi.org/10.1002/marc.201300879	journal	February 2014
Amphiphilic A _x B _y mikto‐arm star copolymers with PLMA and POEGMA arms: Self‐assembly and drug encapsulation Vlassi, Eleni; Papagiannopoulos, Aristeidis; Pispas, Stergios Journal of Polymer Science, Vol. 59, Issue 9 https://doi.org/10.1002/pol.20210082	journal	March 2021
Thermoplastic elastomers Holden, G.; Bishop, E. T.; Legge, N. R. Journal of Polymer Science Part C: Polymer Symposia, Vol. 26, Issue 1 https://doi.org/10.1002/polc.5070260104	journal	January 1969
Square and Rectangular Symmetry Tiles from Bulk and Thin Film 3-Miktoarm Star Terpolymers Aissou, Karim; Nunns, Adam; Manners, Ian Small, Vol. 9, Issue 23 https://doi.org/10.1002/smll.201300657	journal	July 2013
Self-assembled, thermosensitive micelles of a star block copolymer based on PMMA and PNIPAAm for controlled drug delivery Wei, Hua; Zhang, Xianzheng; Cheng, Cheng Biomaterials, Vol. 28, Issue 1 https://doi.org/10.1016/j.biomaterials.2006.08.030	journal	January 2007
Tailoring the efficacy of nimodipine drug delivery using nanocarriers based on A2B miktoarm star polymers Soliman, Ghareb M.; Sharma, Rishi; Choi, Angela O. Biomaterials, Vol. 31, Issue 32 https://doi.org/10.1016/j.biomaterials.2010.07.039	journal	November 2010
Precise Placement of Single Monomer Units in Living Ring-Opening Metathesis Polymerization Elling, Benjamin R.; Su, Jessica K.; Feist, John D. Chem, Vol. 5, Issue 10 https://doi.org/10.1016/j.chempr.2019.07.017	journal	October 2019
Synthesis of ABC-type miktoarm star polymers by “click” chemistry, ATRP and ROP Deng, Guohua; Ma, Deyun; Xu, Zizhen European Polymer Journal, Vol. 43, Issue 4 https://doi.org/10.1016/j.eurpolymj.2007.01.034	journal	April 2007
Successive synthesis of well-defined multiarmed miktoarm star polymers by iterative methodology using living anionic polymerization Ito, Shotaro; Goseki, Raita; Ishizone, Takashi European Polymer Journal, Vol. 49, Issue 9 https://doi.org/10.1016/j.eurpolymj.2013.05.014	journal	September 2013
Core cross-linked star polymers via controlled radical polymerisation Blencowe, Anton; Tan, Jing Fung; Goh, Tor Kit Polymer, Vol. 50, Issue 1 https://doi.org/10.1016/j.polymer.2008.09.049	journal	January 2009
A new approach to 3-miktoarm star polymers using a combination of reversible addition–fragmentation chain transfer (RAFT) and ring opening polymerization (ROP) via “Click” chemistry Vora, Ankit; Singh, Kunal; Webster, Dean C. Polymer, Vol. 50, Issue 13 https://doi.org/10.1016/j.polymer.2009.03.054	journal	June 2009
A novel amphiphilic AB2 star copolymer synthesized by the combination of ring-opening metathesis polymerization and atom transfer radical polymerization Liu, Jingwei; Li, Jinxin; Xie, Meiran Polymer, Vol. 50, Issue 22 https://doi.org/10.1016/j.polymer.2009.09.029	journal	October 2009
A facile chemoenzymatic synthesis of amphiphilic miktoarm star copolymers from a sugar core and their potential for anticancer drug delivery Zhu, Meng-meng; Song, Fei; Nie, Wu-cheng Polymer, Vol. 93 https://doi.org/10.1016/j.polymer.2016.04.035	journal	June 2016
Synthesis of α-d-glucose-based star polymers through simplified electrochemically mediated ATRP Chmielarz, Paweł Polymer, Vol. 102 https://doi.org/10.1016/j.polymer.2016.09.007	journal	October 2016
Living ring-opening metathesis polymerization Bielawski, Christopher W.; Grubbs, Robert H. Progress in Polymer Science, Vol. 32, Issue 1, p. 1-29 https://doi.org/10.1016/j.progpolymsci.2006.08.006	journal	January 2007
Controlled/living radical polymerization: Features, developments, and perspectives Braunecker, Wade A.; Matyjaszewski, Krzysztof Progress in Polymer Science, Vol. 32, Issue 1 https://doi.org/10.1016/j.progpolymsci.2006.11.002	journal	January 2007
Synthesis of functional polymers with controlled architecture by CRP of monomers in the presence of cross-linkers: From stars to gels Gao, Haifeng; Matyjaszewski, Krzysztof Progress in Polymer Science, Vol. 34, Issue 4 https://doi.org/10.1016/j.progpolymsci.2009.01.001	journal	April 2009
Star-shaped polymers having PEO arms Lapienis, Grzegorz Progress in Polymer Science, Vol. 34, Issue 9 https://doi.org/10.1016/j.progpolymsci.2009.04.006	journal	September 2009
Synthesis of well-defined star-branched polymers by stepwise iterative methodology using living anionic polymerization Higashihara, Tomoya; Hayashi, Mayumi; Hirao, Akira Progress in Polymer Science, Vol. 36, Issue 3 https://doi.org/10.1016/j.progpolymsci.2010.08.001	journal	March 2011
Nitroxide-mediated polymerization Nicolas, Julien; Guillaneuf, Yohann; Lefay, Catherine Progress in Polymer Science, Vol. 38, Issue 1 https://doi.org/10.1016/j.progpolymsci.2012.06.002	journal	January 2013
Dendrimer as nanocarrier for drug delivery Kesharwani, Prashant; Jain, Keerti; Jain, Narendra Kumar Progress in Polymer Science, Vol. 39, Issue 2 https://doi.org/10.1016/j.progpolymsci.2013.07.005	journal	February 2014
Star polymers: Advances in biomedical applications Wu, Wei; Wang, Weigang; Li, Jianshu Progress in Polymer Science, Vol. 46 https://doi.org/10.1016/j.progpolymsci.2015.02.002	journal	July 2015
Antimicrobial polymeric nanoparticles Lam, Shu J.; Wong, Edgar H. H.; Boyer, Cyrille Progress in Polymer Science, Vol. 76 https://doi.org/10.1016/j.progpolymsci.2017.07.007	journal	January 2018
Self-assembled nanostructures from amphiphilic block copolymers prepared via ring-opening metathesis polymerization (ROMP) Varlas, Spyridon; Lawrenson, Stefan B.; Arkinstall, Lucy A. Progress in Polymer Science, Vol. 107 https://doi.org/10.1016/j.progpolymsci.2020.101278	journal	August 2020
Reversible-deactivation radical polymerization (Controlled/living radical polymerization): From discovery to materials design and applications Corrigan, Nathaniel; Jung, Kenward; Moad, Graeme Progress in Polymer Science, Vol. 111 https://doi.org/10.1016/j.progpolymsci.2020.101311	journal	December 2020
Cyclodextrin polymers: Structure, synthesis, and use as drug carriers Liu, Zongjian; Ye, Lin; Xi, Jianing Progress in Polymer Science, Vol. 118 https://doi.org/10.1016/j.progpolymsci.2021.101408	journal	July 2021
Recent Fascinating Aspects of the CuAAC Click Reaction Meldal, Morten; Diness, Frederik Trends in Chemistry, Vol. 2, Issue 6 https://doi.org/10.1016/j.trechm.2020.03.007	journal	June 2020
Modulating Antimicrobial Activity and Mammalian Cell Biocompatibility with Glucosamine-Functionalized Star Polymers Wong, Edgar H. H.; Khin, Mya Mya; Ravikumar, Vikashini Biomacromolecules, Vol. 17, Issue 3 https://doi.org/10.1021/acs.biomac.5b01766	journal	February 2016
Star Polymers Ren, Jing M.; McKenzie, Thomas G.; Fu, Qiang Chemical Reviews, Vol. 116, Issue 12 https://doi.org/10.1021/acs.chemrev.6b00008	journal	June 2016
Versatile Approach for Preparing PVC-Based Mikto-Arm Star Additives Based on RAFT Polymerization Sun, Zhonghe; Wang, Mu; Li, Zhi Macromolecules, Vol. 53, Issue 11 https://doi.org/10.1021/acs.macromol.0c00125	journal	May 2020
Tuning Solvent Quality Induces Morphological Phase Transitions in Miktoarm Star Polymer Films Workineh, Zerihun G.; Pellicane, Giuseppe; Tsige, Mesfin Macromolecules, Vol. 53, Issue 15 https://doi.org/10.1021/acs.macromol.0c00770	journal	July 2020
Enhanced Mechanical Properties of Aliphatic Polyester Thermoplastic Elastomers through Star Block Architectures Liffland, Stephanie; Hillmyer, Marc A. Macromolecules, Vol. 54, Issue 20 https://doi.org/10.1021/acs.macromol.1c01357	journal	October 2021
Complex Thin Film Morphologies of Poly(n-hexyl isocyanate)(5k,10k)–Poly(ε-caprolactone)_1–3(10k,17k) Miktoarm Star Polymers Phinjaroenphan, Rarm; Kim, Young Yong; Ree, Brian J. Macromolecules, Vol. 48, Issue 16 https://doi.org/10.1021/acs.macromol.5b00875	journal	August 2015
Visible Light Mediated Controlled Radical Polymerization in the Absence of Exogenous Radical Sources or Catalysts McKenzie, Thomas G.; Fu, Qiang; Wong, Edgar H. H. Macromolecules, Vol. 48, Issue 12 https://doi.org/10.1021/acs.macromol.5b00965	journal	June 2015
Aperiodic “Bricks and Mortar” Mesophase: a New Equilibrium State of Soft Matter and Application as a Stiff Thermoplastic Elastomer Shi, Weichao; Hamilton, Andrew L.; Delaney, Kris T. Macromolecules, Vol. 48, Issue 15 https://doi.org/10.1021/acs.macromol.5b01210	journal	July 2015
50th Anniversary Perspective : RAFT Polymerization—A User Guide Perrier, Sébastien Macromolecules, Vol. 50, Issue 19 https://doi.org/10.1021/acs.macromol.7b00767	journal	September 2017
Brush-First and ROMP-Out with Functional (Macro)monomers: Method Development, Structural Investigations, and Applications of an Expanded Brush-Arm Star Polymer Platform Golder, Matthew R.; Nguyen, Hung V. -T.; Oldenhuis, Nathan J. Macromolecules, Vol. 51, Issue 23 https://doi.org/10.1021/acs.macromol.8b01966	journal	November 2018
Miktoarm Stars via Grafting-Through Copolymerization: Self-Assembly and the Star-to-Bottlebrush Transition Levi, Adam E.; Lequieu, Joshua; Horne, Jacob D. Macromolecules, Vol. 52, Issue 4 https://doi.org/10.1021/acs.macromol.8b02321	journal	February 2019
Extreme Deflection of Phase Boundaries and Chain Bridging in A(BA′) _n Miktoarm Star Polymers Lequieu, Joshua; Koeper, Trenton; Delaney, Kris T. Macromolecules, Vol. 53, Issue 2 https://doi.org/10.1021/acs.macromol.9b02254	journal	January 2020
Efficient Synthesis of Asymmetric Miktoarm Star Polymers Levi, Adam E.; Fu, Liangbing; Lequieu, Joshua Macromolecules, Vol. 53, Issue 2 https://doi.org/10.1021/acs.macromol.9b02380	journal	January 2020
Hydrophilic Stars, Amphiphilic Star Block Copolymers, and Miktoarm Stars with Degradable Polycarbonate Cores Augustine, Dhanya; Hadjichristidis, Nikos; Gnanou, Yves Macromolecules, Vol. 53, Issue 3 https://doi.org/10.1021/acs.macromol.9b02658	journal	January 2020
A Novel Poly(vinylidene fluoride)-Based 4-Miktoarm Star Terpolymer: Synthesis and Self-Assembly Patil, Yogesh; Bilalis, Panayiotis; Polymeropoulos, George Molecular Pharmaceutics, Vol. 15, Issue 8 https://doi.org/10.1021/acs.molpharmaceut.8b00010	journal	March 2018
Optimization of Amphiphilic Miktoarm Star Copolymers for Anticancer Drug Delivery Wang, Mingqi; Zhang, Xiaolong; Peng, Han ACS Biomaterials Science & Engineering, Vol. 4, Issue 8 https://doi.org/10.1021/acsbiomaterials.8b00678	journal	July 2018
Synthesis and Self-Assembly of AB _n Miktoarm Star Polymers Bates, Morgan W.; Barbon, Stephanie M.; Levi, Adam E. ACS Macro Letters, Vol. 9, Issue 3 https://doi.org/10.1021/acsmacrolett.0c00061	journal	February 2020
Controlled Formation of Star Polymer Nanoparticles via Visible Light Photopolymerization McKenzie, Thomas G.; Wong, Edgar H. H.; Fu, Qiang ACS Macro Letters, Vol. 4, Issue 9 https://doi.org/10.1021/acsmacrolett.5b00530	journal	August 2015
Multi-Dimensional Self-Assembly of a Dual-Responsive ABC Miktoarm Star Terpolymer Xu, Fugui; Wu, Dongdong; Huang, Yinjuan ACS Macro Letters, Vol. 6, Issue 4 https://doi.org/10.1021/acsmacrolett.7b00031	journal	March 2017
Mikto-Brush-Arm Star Polymers via Cross-Linking of Dissimilar Bottlebrushes: Synthesis and Solution Morphologies Shibuya, Yoshiki; Nguyen, Hung V. -T.; Johnson, Jeremiah A. ACS Macro Letters, Vol. 6, Issue 9 https://doi.org/10.1021/acsmacrolett.7b00529	journal	August 2017
Efficient and Facile End Group Control of Living Ring-Opening Metathesis Polymers via Single Addition of Functional Cyclopropenes Elling, Benjamin R.; Xia, Yan ACS Macro Letters, Vol. 7, Issue 6 https://doi.org/10.1021/acsmacrolett.8b00347	journal	May 2018
Solid-State Polymer Electrolytes Based on AB ₃ -Type Miktoarm Star Copolymers Lee, Daeyeon; Jung, Ha Young; Park, Moon Jeong ACS Macro Letters, Vol. 7, Issue 8 https://doi.org/10.1021/acsmacrolett.8b00474	journal	August 2018
Synthesis of Multicompartment Nanoparticles of ABC Miktoarm Star Polymers by Seeded RAFT Dispersion Polymerization Li, Shenzhen; Nie, Huijun; Gu, Song ACS Macro Letters, Vol. 8, Issue 7 https://doi.org/10.1021/acsmacrolett.9b00371	journal	June 2019
Hyperbranched Polyglycerols: From the Controlled Synthesis of Biocompatible Polyether Polyols to Multipurpose Applications Wilms, Daniel; Stiriba, Salah-Eddine; Frey, Holger Accounts of Chemical Research, Vol. 43, Issue 1 https://doi.org/10.1021/ar900158p	journal	September 2009
Additivity rules for the estimation of thermochemical properties Benson, Sidney W.; Cruickshank, F. R.; Golden, D. M. Chemical Reviews, Vol. 69, Issue 3 https://doi.org/10.1021/cr60259a002	journal	June 1969
Atom Transfer Radical Polymerization Matyjaszewski, Krzysztof; Xia, Jianhui Chemical Reviews, Vol. 101, Issue 9 https://doi.org/10.1021/cr940534g	journal	September 2001
Controlled/"living" radical polymerization. atom transfer radical polymerization in the presence of transition-metal complexes Wang, Jin-Shan; Matyjaszewski, Krzysztof Journal of the American Chemical Society, Vol. 117, Issue 20 https://doi.org/10.1021/ja00125a035	journal	May 1995
Low Polydispersity Star Polymers via Cross-Linking Macromonomers by ATRP Gao, Haifeng; Ohno, Shigeki; Matyjaszewski, Krzysztof Journal of the American Chemical Society, Vol. 128, Issue 47 https://doi.org/10.1021/ja066964t	journal	November 2006
Arm-First Method As a Simple and General Method for Synthesis of Miktoarm Star Copolymers Gao, Haifeng; Matyjaszewski, Krzysztof Journal of the American Chemical Society, Vol. 129, Issue 38 https://doi.org/10.1021/ja073690g	journal	September 2007
Synthesis of Oligo(thiophene)-Coated Star-Shaped ROMP Polymers: Unique Emission Properties by the Precise Integration of Functionality Takamizu, Kenji; Nomura, Kotohiro Journal of the American Chemical Society, Vol. 134, Issue 18 https://doi.org/10.1021/ja301526v	journal	April 2012
“Brush-First” Method for the Parallel Synthesis of Photocleavable, Nitroxide-Labeled Poly(ethylene glycol) Star Polymers Liu, Jenny; Burts, Alan O.; Li, Yongjun Journal of the American Chemical Society, Vol. 134, Issue 39 https://doi.org/10.1021/ja3067176	journal	September 2012
New Method To Access Hyperbranched Polymers with Uniform Structure via One-Pot Polymerization of Inimer in Microemulsion Min, Ke; Gao, Haifeng Journal of the American Chemical Society, Vol. 134, Issue 38 https://doi.org/10.1021/ja307174h	journal	September 2012
Living Alternating Ring-Opening Metathesis Polymerization Based on Single Monomer Additions Elling, Benjamin R.; Xia, Yan Journal of the American Chemical Society, Vol. 137, Issue 31 https://doi.org/10.1021/jacs.5b05497	journal	July 2015
Relay Conjugation of Living Metathesis Polymers Fu, Liangbing; Zhang, Tianqi; Fu, Guanyao Journal of the American Chemical Society, Vol. 140, Issue 38 https://doi.org/10.1021/jacs.8b07315	journal	August 2018
Depolymerization of Bottlebrush Polypentenamers and Their Macromolecular Metamorphosis Neary, William J.; Isais, Taylor A.; Kennemur, Justin G. Journal of the American Chemical Society, Vol. 141, Issue 36 https://doi.org/10.1021/jacs.9b05560	journal	August 2019
Grafting from Surfaces for “Everyone”: ARGET ATRP in the Presence of Air Matyjaszewski, Krzysztof; Dong, Hongchen; Jakubowski, Wojciech Langmuir, Vol. 23, Issue 8 https://doi.org/10.1021/la063402e	journal	April 2007
Synthesis of amphiphilic star block copolymers using ring-opening metathesis polymerization Saunders, Randall S.; Cohen, Robert E.; Wong, Seit Jean Macromolecules, Vol. 25, Issue 7 https://doi.org/10.1021/ma00033a035	journal	March 1992
Polymerization of Methyl Methacrylate with the Carbon Tetrachloride/Dichlorotris- (triphenylphosphine)ruthenium(II)/Methylaluminum Bis(2,6-di-tert-butylphenoxide) Initiating System: Possibility of Living Radical Polymerization Kato, Mitsuru; Kamigaito, Masami; Sawamoto, Mitsuo Macromolecules, Vol. 28, Issue 5 https://doi.org/10.1021/ma00109a056	journal	September 1995
Effects of polydispersity in the end-grafted polymer brush Milner, S. T.; Witten, T. A.; Cates, M. E. Macromolecules, Vol. 22, Issue 2 https://doi.org/10.1021/ma00192a057	journal	March 1989
Synthesis of Amphiphilic Miktoarm ABC Star Copolymers by RAFT Mechanism Using Maleic Anhydride as Linking Agent Feng, Xiao-Shuang; Pan, Cai-Yuan Macromolecules, Vol. 35, Issue 13 https://doi.org/10.1021/ma020004j	journal	May 2002
Micelles of Star Block (PSPI)₈ and PSPI Diblock Copolymers (PS = Polystyrene, PI = Polyisoprene): Structure and Kinetics of Micellization Mountrichas, Grigoris; Mpiri, Maria; Pispas, Stergios Macromolecules, Vol. 38, Issue 3 https://doi.org/10.1021/ma047937v	journal	January 2005
Interfaces in Diblocks: A Study of Miktoarm Star Copolymers Grason, Gregory M.; Kamien, Randall D. Macromolecules, Vol. 37, Issue 19 https://doi.org/10.1021/ma049255d	journal	September 2004
Synthesis of Degradable Miktoarm Star Copolymers via Atom Transfer Radical Polymerization Gao, Haifeng; Tsarevsky, Nicolay V.; Matyjaszewski, Krzysztof Macromolecules, Vol. 38, Issue 14 https://doi.org/10.1021/ma0503099	journal	July 2005
Activators Regenerated by Electron Transfer for Atom Transfer Radical Polymerization of Styrene Jakubowski, Wojciech; Min, Ke; Matyjaszewski, Krzysztof Macromolecules, Vol. 39, Issue 1 https://doi.org/10.1021/ma0522716	journal	January 2006
Degradable Core Cross-Linked Star Polymers via Ring-Opening Polymerization Wiltshire, James T.; Qiao, Greg G. Macromolecules, Vol. 39, Issue 13 https://doi.org/10.1021/ma060712v	journal	June 2006
Synthesis of Miktoarm Star Polymers via ATRP Using the “In−Out” Method: Determination of Initiation Efficiency of Star Macroinitiators Gao, Haifeng; Matyjaszewski, Krzysztof Macromolecules, Vol. 39, Issue 21 https://doi.org/10.1021/ma061702x	journal	October 2006
Synthesis of Star Polymers Using ARGET ATRP Burdyńska, Joanna; Cho, Hong Y.; Mueller, Laura Macromolecules, Vol. 43, Issue 22 https://doi.org/10.1021/ma101971z	journal	November 2010
RAFT Agent Design and Synthesis Keddie, Daniel J.; Moad, Graeme; Rizzardo, Ezio Macromolecules, Vol. 45, Issue 13 https://doi.org/10.1021/ma300410v	journal	May 2012
Versatile Synthesis of Multiarm and Miktoarm Star Polymers with a Branched Core by Combination of Menschutkin Reaction and Controlled Polymerization Zhang, Meijing; Liu, Huanhuan; Shao, Wei Macromolecules, Vol. 45, Issue 23 https://doi.org/10.1021/ma301973v	journal	November 2012
Block Copolymer Lithography Bates, Christopher M.; Maher, Michael J.; Janes, Dustin W. Macromolecules, Vol. 47, Issue 1, p. 2-12 https://doi.org/10.1021/ma401762n	journal	November 2013
Toward Strong Thermoplastic Elastomers with Asymmetric Miktoarm Block Copolymer Architectures Shi, Weichao; Lynd, Nathaniel A.; Montarnal, Damien Macromolecules, Vol. 47, Issue 6 https://doi.org/10.1021/ma402566g	journal	March 2014
A Novel Photoresponsive Azobenzene-Containing Miktoarm Star Polymer: Self-Assembly and Photoresponse Properties Blasco, Eva; Schmidt, Bernhard V. K. J.; Barner-Kowollik, Christopher Macromolecules, Vol. 47, Issue 11 https://doi.org/10.1021/ma500254p	journal	May 2014
“Click”-Inspired Chemistry in Macromolecular Science: Matching Recent Progress and User Expectations Espeel, Pieter; Du Prez, Filip E. Macromolecules, Vol. 48, Issue 1 https://doi.org/10.1021/ma501386v	journal	November 2014
Hierarchical Structures in Thin Films of Miktoarm Star Polymers: Poly(n-hexyl isocyanate)(12K)–Poly(ε-caprolactone)_1–3(5K) Kim, Young Yong; Jung, Sungmin; Kim, Changsub Macromolecules, Vol. 47, Issue 21 https://doi.org/10.1021/ma501695b	journal	October 2014
Highly Efficient and Versatile Formation of Biocompatible Star Polymers in Pure Water and Their Stimuli-Responsive Self-Assembly McKenzie, Thomas G.; Wong, Edgar H. H.; Fu, Qiang Macromolecules, Vol. 47, Issue 22 https://doi.org/10.1021/ma502008j	journal	November 2014
Synthesis of Thermoresponsive Mixed Arm Star Polymers by Combination of RAFT and ATRP from a Multifunctional Core and Its Self-Assembly in Water Ranganathan, Krishnan; Deng, Rui; Kainthan, Rajesh K. Macromolecules, Vol. 41, Issue 12 https://doi.org/10.1021/ma800094d	journal	June 2008
Synthesis of Low-Polydispersity Miktoarm Star Copolymers via a Simple “Arm-First” Method: Macromonomers as Arm Precursors Gao, Haifeng; Matyjaszewski, Krzysztof Macromolecules, Vol. 41, Issue 12 https://doi.org/10.1021/ma800618d	journal	June 2008
Facile Controlled Synthesis of Soluble Star Shape Polymers by Ring-Opening Metathesis Polymerization (ROMP) Nomura, Kotohiro; Watanabe, Yu; Fujita, Sakiko Macromolecules, Vol. 42, Issue 4 https://doi.org/10.1021/ma8027529	journal	January 2009
Design of Soft and Strong Thermoplastic Elastomers Based on Nonlinear Block Copolymer Architectures Using Self-Consistent-Field Theory Lynd, Nathaniel A.; Oyerokun, Folusho T.; O’Donoghue, Donal L. Macromolecules, Vol. 43, Issue 7 https://doi.org/10.1021/ma902517v	journal	April 2010
Living Free-Radical Polymerization by Reversible Addition−Fragmentation Chain Transfer: The RAFT Process Chiefari, John; Chong, Y. K. (Bill); Ercole, Frances Macromolecules, Vol. 31, Issue 16 https://doi.org/10.1021/ma9804951	journal	August 1998
Organic Catalyst-Mediated Ring-Opening Polymerization for the Highly Efficient Synthesis of Polyester-Based Star Polymers Ren, Jing M.; Fu, Qiang; Blencowe, Anton ACS Macro Letters, Vol. 1, Issue 6 https://doi.org/10.1021/mz300169m	journal	May 2012
Complex Self-Assembled Morphologies of Thin Films of an Asymmetric A₃B₃C₃ Star Polymer Rho, Yecheol; Kim, Changsub; Higashihara, Tomoya ACS Macro Letters, Vol. 2, Issue 10 https://doi.org/10.1021/mz400363k	journal	September 2013
Multicompartment Micelle Morphology Evolution in Degradable Miktoarm Star Terpolymers Saito, Naohiko; Liu, Chun; Lodge, Timothy P. ACS Nano, Vol. 4, Issue 4 https://doi.org/10.1021/nn9016873	journal	March 2010
Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers Lam, Shu J.; O'Brien-Simpson, Neil M.; Pantarat, Namfon Nature Microbiology, Vol. 1, Issue 11 https://doi.org/10.1038/nmicrobiol.2016.162	journal	September 2016
Marrying click chemistry with polymerization: expanding the scope of polymeric materials Golas, Patricia L.; Matyjaszewski, Krzysztof Chem. Soc. Rev., Vol. 39, Issue 4 https://doi.org/10.1039/B901978M	journal	January 2010
Precise synthesis of a rod-coil type miktoarm star copolymer containing poly(n-hexyl isocyanate) and aliphatic polyester Satoh, Toshifumi; Nishikawa, Naoki; Kawato, Daisuke Polym. Chem., Vol. 5, Issue 2 https://doi.org/10.1039/C3PY00985H	journal	January 2014
Synthesis, postmodification and fluorescence properties of reduction-cleavable core-couplable miktoarm stars with a branched core Li, Cangxia; Liu, Huanhuan; Tang, Dandan Polymer Chemistry, Vol. 6, Issue 9 https://doi.org/10.1039/C4PY01495B	journal	January 2015
CO₂-Stimulated morphology transition of ABC miktoarm star terpolymer assemblies Huo, Meng; Du, Haotian; Zeng, Min Polymer Chemistry, Vol. 8, Issue 18 https://doi.org/10.1039/C7PY00214A	journal	January 2017
Recent advances in ruthenium-based olefin metathesis Ogba, O. M.; Warner, N. C.; O’Leary, D. J. Chemical Society Reviews, Vol. 47, Issue 12 https://doi.org/10.1039/C8CS00027A	journal	January 2018
Synthesis of multifunctional miktoarm star polymers via an RGD peptide-based RAFT agent Chen, Chao; Guo, Xiaofeng; Du, Jinhong Polymer Chemistry, Vol. 10, Issue 2 https://doi.org/10.1039/C8PY01355A	journal	January 2019
Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids Rasines Mazo, Alicia; Allison-Logan, Stephanie; Karimi, Fatemeh Chemical Society Reviews, Vol. 49, Issue 14 https://doi.org/10.1039/C9CS00738E	journal	January 2020
Click chemistry: function follows form Finn, M. G.; Fokin, Valery V. Chemical Society Reviews, Vol. 39, Issue 4 https://doi.org/10.1039/c003740k	journal	January 2010
Miktoarm star polymers: advances in synthesis, self-assembly, and applications Khanna, Kunal; Varshney, Sunil; Kakkar, Ashok Polymer Chemistry, Vol. 1, Issue 8 https://doi.org/10.1039/c0py00082e	journal	January 2010
Synthesis of ABC type miktoarm star copolymers by triple click chemistry Iskin, Birol; Yilmaz, Gorkem; Yagci, Yusuf Polymer Chemistry, Vol. 2, Issue 12 https://doi.org/10.1039/c1py00352f	journal	January 2011
Toward biodegradable nanogel star polymers via organocatalytic ROP Appel, Eric A.; Lee, Victor Y.; Nguyen, Timothy T. Chemical Communications, Vol. 48, Issue 49 https://doi.org/10.1039/c2cc31406a	journal	January 2012
Quantitative formation of core cross-linked star polymers via a one-pot two-step single electron transfer-living radical polymerization Wong, Edgar H. H.; Blencowe, Anton; Qiao, Greg G. Polymer Chemistry, Vol. 4, Issue 17 https://doi.org/10.1039/c3py00726j	journal	January 2013
Amphiphilic miktoarm star copolymer (PCL)3-(PDEAEMA-b-PPEGMA)3 as pH-sensitive micelles in the delivery of anticancer drug Lin, Wenjing; Nie, Shuyu; Zhong, Qi Journal of Materials Chemistry B, Vol. 2, Issue 25 https://doi.org/10.1039/c3tb21694b	journal	January 2014
Equilibrium behavior of asymmetric ABA triblock copolymer melts Matsen, M. W. The Journal of Chemical Physics, Vol. 113, Issue 13 https://doi.org/10.1063/1.1289889	journal	January 2000
Synthesis of Star Polymers using RAFT Polymerization: What is Possible? Barner-Kowollik, Christopher; Davis, Thomas P.; Stenzel, Martina H. Australian Journal of Chemistry, Vol. 59, Issue 10 https://doi.org/10.1071/CH06297	journal	January 2006
The role of miktoarm star copolymers in drug delivery systems Aghajanzadeh, Mozhgan; Zamani, Mostafa; Rostamizadeh, Kobra Journal of Macromolecular Science, Part A, Vol. 55, Issue 7 https://doi.org/10.1080/10601325.2018.1483200	journal	July 2018
Multicompartment Micelles from ABC Miktoarm Stars in Water Li, Z. Science, Vol. 306, Issue 5693 https://doi.org/10.1126/science.1103350	journal	October 2004
Electrochemically Mediated Atom Transfer Radical Polymerization Magenau, A. J. D.; Strandwitz, N. C.; Gennaro, A. Science, Vol. 332, Issue 6025 https://doi.org/10.1126/science.1202357	journal	March 2011
Miktoarm Star Polymers: Branched Architectures in Drug Delivery Lotocki, Victor; Kakkar, Ashok Pharmaceutics, Vol. 12, Issue 9 https://doi.org/10.3390/pharmaceutics12090827	journal	August 2020
Ring-Opening Polymerization—An Introductory Review Nuyken, Oskar; Pask, Stephen Polymers, Vol. 5, Issue 2, p. 361-403 https://doi.org/10.3390/polym5020361	journal	April 2013

Similar Records

Asymmetric Miktoarm Star Polymers as Polyester Thermoplastic Elastomers

Journal Article · 2022 · Macromolecules · OSTI ID:1971662

Blankenship, Jacob R.; Levi, Adam E.; Goldfeld, David J.; +5 more

Efficient Synthesis of Asymmetric Miktoarm Star Polymers

Journal Article · 2020 · Macromolecules · OSTI ID:1594104

Levi, Adam E.; Fu, Liangbing; Lequieu, Joshua; +7 more

Miktoarm Stars via Grafting-Through Copolymerization: Self-Assembly and the Star-to-Bottlebrush Transition

Journal Article · 2019 · Macromolecules · OSTI ID:1594102

Levi, Adam E.; Lequieu, Joshua; Horne, Jacob D.; +5 more

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Polymers
RAFT polymerization
Radical polymerization
Ring-opening polymerization
Star polymers

Title: Miktoarm Star Polymers: Synthesis and Applications

Citation Formats

References (116)

Similar Records

Related Subjects