Differential Age Effects of Transcranial Direct Current Stimulation on Associative Memory
Abstract
Abstract Objectives Older adults experience associative memory deficits relative to younger adults (Old & Naveh-Benjamin, 2008). The aim of this study was to test the effect of transcranial direct current stimulation (tDCS) on face-name associative memory in older and younger adults. Method Experimenters applied active (1.5 mA) or sham (0.1 mA) stimulation with the anode placed over the left dorsolateral prefrontal cortex (dlPFC) during a face-name encoding task, and measured both cued recall and recognition performance. Participants completed memory tests immediately after stimulation and after a 24-h delay to examine both immediate and delayed stimulation effects on memory. Results Results showed improved face-name associative memory performance for both recall and recognition measures, but only for younger adults, whereas there was no difference between active and sham stimulation for older adults. For younger adults, stimulation-induced memory improvements persisted after a 24-h delay, suggesting delayed effects of tDCS after a consolidation period. Discussion Although effective in younger adults, these results suggest that older adults may be resistant to this intervention, at least under the stimulation parameters used in the current study. This finding is inconsistent with a commonly seen trend, where tDCS effects on cognition are larger in older than younger adults.
- Authors:
-
- Loyola University Chicago
- University of Illinois at Chicago
- Sandia National Laboratories
- Publication Date:
- Sponsoring Org.:
- USDOE National Nuclear Security Administration (NNSA)
- OSTI Identifier:
- 1562341
- Grant/Contract Number:
- NA0003525
- Resource Type:
- Published Article
- Journal Name:
- The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
- Additional Journal Information:
- Journal Name: The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences Journal Volume: 74 Journal Issue: 7; Journal ID: ISSN 1079-5014
- Publisher:
- Oxford University Press
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Leach, Ryan C., McCurdy, Matthew P., Trumbo, Michael C., Matzen, Laura E., Leshikar, Eric D., and Anderson, ed., Nicole. Differential Age Effects of Transcranial Direct Current Stimulation on Associative Memory. United States: N. p., 2018.
Web. doi:10.1093/geronb/gby003.
Leach, Ryan C., McCurdy, Matthew P., Trumbo, Michael C., Matzen, Laura E., Leshikar, Eric D., & Anderson, ed., Nicole. Differential Age Effects of Transcranial Direct Current Stimulation on Associative Memory. United States. https://doi.org/10.1093/geronb/gby003
Leach, Ryan C., McCurdy, Matthew P., Trumbo, Michael C., Matzen, Laura E., Leshikar, Eric D., and Anderson, ed., Nicole. Thu .
"Differential Age Effects of Transcranial Direct Current Stimulation on Associative Memory". United States. https://doi.org/10.1093/geronb/gby003.
@article{osti_1562341,
title = {Differential Age Effects of Transcranial Direct Current Stimulation on Associative Memory},
author = {Leach, Ryan C. and McCurdy, Matthew P. and Trumbo, Michael C. and Matzen, Laura E. and Leshikar, Eric D. and Anderson, ed., Nicole},
abstractNote = {Abstract Objectives Older adults experience associative memory deficits relative to younger adults (Old & Naveh-Benjamin, 2008). The aim of this study was to test the effect of transcranial direct current stimulation (tDCS) on face-name associative memory in older and younger adults. Method Experimenters applied active (1.5 mA) or sham (0.1 mA) stimulation with the anode placed over the left dorsolateral prefrontal cortex (dlPFC) during a face-name encoding task, and measured both cued recall and recognition performance. Participants completed memory tests immediately after stimulation and after a 24-h delay to examine both immediate and delayed stimulation effects on memory. Results Results showed improved face-name associative memory performance for both recall and recognition measures, but only for younger adults, whereas there was no difference between active and sham stimulation for older adults. For younger adults, stimulation-induced memory improvements persisted after a 24-h delay, suggesting delayed effects of tDCS after a consolidation period. Discussion Although effective in younger adults, these results suggest that older adults may be resistant to this intervention, at least under the stimulation parameters used in the current study. This finding is inconsistent with a commonly seen trend, where tDCS effects on cognition are larger in older than younger adults.},
doi = {10.1093/geronb/gby003},
journal = {The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences},
number = 7,
volume = 74,
place = {United States},
year = {Thu Feb 01 00:00:00 EST 2018},
month = {Thu Feb 01 00:00:00 EST 2018}
}
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