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Title: Transcranial stimulation over the left inferior frontal gyrus increases false alarms in an associative memory task in older adults

Here, transcranial direct current stimulation (tDCS) is a potent ial tool for alleviating various forms of cognitive decline, including memory loss, in older adults. However, past effects of tDCS on cognitive ability have been mixed. One important potential moderator of tDCS effects is the baseline level of cognitive performance. We tested the effects of tDCS on face-name associative memory in older adults, who suffer from performance deficits in this task relative to younger adults. Stimulation was applied to the left inferior prefrontal cortex during encoding of face-name pairs, and memory was assessed with both a recognition and recall task. As a result, face–name memory performance was decreased with the use of tDCS. This result was driven by increased false alarms when recognizing rearranged face–name pairs.
Authors:
 [1] ;  [1] ;  [2] ;  [3] ;  [1]
  1. Univ. of Illinois, Chicago, IL (United States)
  2. Univ. of New Mexico, Albuquerque, NM (United States)
  3. Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Publication Date:
Report Number(s):
SAND-2016-8019J
Journal ID: ISSN 2261-7434; 646704
Grant/Contract Number:
AC04-94AL85000
Type:
Accepted Manuscript
Journal Name:
Healthy Aging Research
Additional Journal Information:
Journal Volume: 5; Journal ID: ISSN 2261-7434
Research Org:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Org:
USDOE National Nuclear Security Administration (NNSA)
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES
OSTI Identifier:
1338318