A process for the separation and purification of yttrium-90 for medical applications
Abstract
An extraction chromatographic method for the preparation of {sup 90}Y of high chemical and radiochemical purity is disclosed. After an initial purification of a {sup 90}Sr stock solution and a suitable period of {sup 90}Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the {sup 90}Sr content of the mixture by a factor of about 10{sup 3}. The {sup 90}Y remaining is freed from any residual {sup 90}Sr, from its {sup 90}Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 97209
- Patent Number(s):
- 8095555
- Application Number:
- ON: DE95017129; PAN: 8-095,555
- Assignee:
- ANL; SCA: 550604; 400201; PA: EDB-95:126463; NTS-96:001553; ERA-20:027650; SN: 95001445197
- Patent Classifications (CPCs):
-
G - PHYSICS G06 - COMPUTING G06F - ELECTRIC DIGITAL DATA PROCESSING
- DOE Contract Number:
- W-31-109-ENG-38
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 1993 Jul 26; Other Information: PBD: 1993; Related Information: U. S. Patent No. 5,368,736. Filed 11/29/1994.
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; 40 CHEMISTRY; YTTRIUM 90; CHEMICAL PREPARATION; INVENTIONS; DESIGN; PURIFICATION; STRONTIUM 90; EXTRACTION; RADIOTHERAPY
Citation Formats
Horwitz, P E, and Dietz, M L. A process for the separation and purification of yttrium-90 for medical applications. United States: N. p., 1993.
Web.
Horwitz, P E, & Dietz, M L. A process for the separation and purification of yttrium-90 for medical applications. United States.
Horwitz, P E, and Dietz, M L. Fri .
"A process for the separation and purification of yttrium-90 for medical applications". United States. https://www.osti.gov/servlets/purl/97209.
@article{osti_97209,
title = {A process for the separation and purification of yttrium-90 for medical applications},
author = {Horwitz, P E and Dietz, M L},
abstractNote = {An extraction chromatographic method for the preparation of {sup 90}Y of high chemical and radiochemical purity is disclosed. After an initial purification of a {sup 90}Sr stock solution and a suitable period of {sup 90}Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the {sup 90}Sr content of the mixture by a factor of about 10{sup 3}. The {sup 90}Y remaining is freed from any residual {sup 90}Sr, from its {sup 90}Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Jan 01 00:00:00 EST 1993},
month = {Fri Jan 01 00:00:00 EST 1993}
}
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