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Title: Process for the separation and purification of yttrium-90 for medical applications

Abstract

An extraction chromatographic method for the preparation of .sup.90 Y of high chemical and radiochemical purity is disclosed. After an initial purification of a .sup.90 Sr stock solution and a suitable period of .sup.90 Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the .sup.90 Sr content of the mixture by a factor of about 10.sup.3. The .sup.90 Y remaining is freed from any residual .sup.90 Sr, from its .sup.90 Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.

Inventors:
 [1];  [2]
  1. (Naperville, IL)
  2. (Evanston, IL)
Issue Date:
Research Org.:
Argonne National Laboratory (ANL), Argonne, IL
OSTI Identifier:
869624
Patent Number(s):
5368736
Assignee:
United States of America as represented by United States (Washington, DC) ANL
DOE Contract Number:  
W-31109-ENG-38
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
process; separation; purification; yttrium-90; medical; applications; extraction; chromatographic; method; preparation; 90; chemical; radiochemical; purity; disclosed; initial; sr; stock; solution; suitable; period; ingrowth; passed; series; strontium-selective; columns; lowers; content; mixture; factor; 10; remaining; freed; residual; zr; daughter; impurities; passing; sample; final; column; designed; selectively; retain; yttrium; medical applications; chromatographic column; extraction chromatographic; /210/423/

Citation Formats

Horwitz, Philip E., and Dietz, Mark L. Process for the separation and purification of yttrium-90 for medical applications. United States: N. p., 1994. Web.
Horwitz, Philip E., & Dietz, Mark L. Process for the separation and purification of yttrium-90 for medical applications. United States.
Horwitz, Philip E., and Dietz, Mark L. Sat . "Process for the separation and purification of yttrium-90 for medical applications". United States. https://www.osti.gov/servlets/purl/869624.
@article{osti_869624,
title = {Process for the separation and purification of yttrium-90 for medical applications},
author = {Horwitz, Philip E. and Dietz, Mark L.},
abstractNote = {An extraction chromatographic method for the preparation of .sup.90 Y of high chemical and radiochemical purity is disclosed. After an initial purification of a .sup.90 Sr stock solution and a suitable period of .sup.90 Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the .sup.90 Sr content of the mixture by a factor of about 10.sup.3. The .sup.90 Y remaining is freed from any residual .sup.90 Sr, from its .sup.90 Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1994},
month = {1}
}

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