Process for the separation and purification of yttrium-90 for medical applications

Title: Process for the separation and purification of yttrium-90 for medical applications

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Abstract

An extraction chromatographic method for the preparation of .sup.90 Y of high chemical and radiochemical purity is disclosed. After an initial purification of a .sup.90 Sr stock solution and a suitable period of .sup.90 Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the .sup.90 Sr content of the mixture by a factor of about 10.sup.3. The .sup.90 Y remaining is freed from any residual .sup.90 Sr, from its .sup.90 Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.

Inventors:

Horwitz, Philip E ^[1]; Dietz, Mark L ^[2]

Naperville, IL
Evanston, IL

Issue Date:: 1994-01-01

Research Org.:: Argonne National Laboratory (ANL), Argonne, IL

OSTI Identifier:: 869624

Patent Number(s):: 5368736

Assignee:: United States of America as represented by United States (Washington, DC)

DOE Contract Number:: W-31109-ENG-38

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: process; separation; purification; yttrium-90; medical; applications; extraction; chromatographic; method; preparation; 90; chemical; radiochemical; purity; disclosed; initial; sr; stock; solution; suitable; period; ingrowth; passed; series; strontium-selective; columns; lowers; content; mixture; factor; 10; remaining; freed; residual; zr; daughter; impurities; passing; sample; final; column; designed; selectively; retain; yttrium; medical applications; chromatographic column; extraction chromatographic; /210/423/

Citation Formats


                    Horwitz, Philip E, and Dietz, Mark L. Process for the separation and purification of yttrium-90 for medical applications.  United States: N. p., 1994. 
        Web.

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                    Horwitz, Philip E, & Dietz, Mark L. Process for the separation and purification of yttrium-90 for medical applications.  United States.

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                    Horwitz, Philip E, and Dietz, Mark L. Sat .  
        "Process for the separation and purification of yttrium-90 for medical applications".  United States.  https://www.osti.gov/servlets/purl/869624.

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@article{osti_869624,

  title        = {Process for the separation and purification of yttrium-90 for medical applications},

  author       = {Horwitz, Philip E and Dietz, Mark L},

  abstractNote = {An extraction chromatographic method for the preparation of .sup.90 Y of high chemical and radiochemical purity is disclosed. After an initial purification of a .sup.90 Sr stock solution and a suitable period of .sup.90 Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the .sup.90 Sr content of the mixture by a factor of about 10.sup.3. The .sup.90 Y remaining is freed from any residual .sup.90 Sr, from its .sup.90 Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1994},

  month        = {1}

}

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