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Title: Biomimetic Hydrogel Materials

Abstract

Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.

Inventors:
 [1]
  1. (Albany, CA), Mukkamala, Ravindranath (Houston, TX), Chen, Oing (Albany, CA), Hu, Hopin (Albuquerque, NM), Baude, Dominique (Creteil, FR)
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
OSTI Identifier:
879652
Patent Number(s):
6552103
Application Number:
09/574938
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61L - METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08F - MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Bertozzi, Carolyn. Biomimetic Hydrogel Materials. United States: N. p., 2003. Web.
Bertozzi, Carolyn. Biomimetic Hydrogel Materials. United States.
Bertozzi, Carolyn. Tue . "Biomimetic Hydrogel Materials". United States. https://www.osti.gov/servlets/purl/879652.
@article{osti_879652,
title = {Biomimetic Hydrogel Materials},
author = {Bertozzi, Carolyn},
abstractNote = {Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 22 00:00:00 EDT 2003},
month = {Tue Apr 22 00:00:00 EDT 2003}
}

Works referenced in this record:

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Synthesis of Sulfated Neoglycopolymers:  Selective P-Selectin Inhibitors
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Inhibition of influenza A virus hemagglutinin and induction of interferon by synthetic sialylated glycoconjugates
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Hepatocyte adhesion to carbohydrate-derivatized surfaces. I. Surface topography of the rat hepatic lectin.
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On the wettability of poly(2-hydroxyethylmethacrylate)
journal, March 1992


Synthetic polymeric sialoside inhibitors of influenza virus receptor-binding activity
journal, October 1990


Protein adsorption on a copolymer having pendant monosaccharide groups. Relationship between surface free energy and protein adsorption
journal, November 1994