Biomimetic hydrogel materials

Bertozzi, Carolyn; Mukkamala, Ravindranath; Chen, Qing; Hu, Hopin; Baude, Dominique

Title: Biomimetic hydrogel materials

Abstract

Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.

Inventors:

Bertozzi, Carolyn ^[1]; Mukkamala, Ravindranath ^[2]; Chen, Qing ^[1]; Hu, Hopin ^[3]; Baude, Dominique ^[4]

Albany, CA
Houston, TX
Albuquerque, NM
Creteil, FR

Issue Date:: 2000-01-01

Research Org.:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

OSTI Identifier:: 873177

Patent Number(s):: 6107365

Assignee:: Regents of University of California (Oakland, CA)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61L - METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL

C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08F - MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61L - METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
A61L2430/16 - for reconstruction of eye parts, e.g. intraocular lens, cornea
A61L27/16 - obtained by reactions only involving carbon-to-carbon unsaturated bonds
A61L27/52 - Hydrogels or hydrocolloids

C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08F - MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
C08F220/382 - {and containing oxygen, e.g. 2-sulfoethyl
C08F220/54 - Amides {, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide}

C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08L - COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
C08L33/14 - of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
C08L51/02 - grafted on to polysaccharides

G - PHYSICS G02 - OPTICS G02B - OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
G02B1/043 - {Contact lenses}

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S524/916 - Hydrogel compositions

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DOE Contract Number:: AC03-76SF00098

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: biomimetic; hydrogel; materials; novel; methods; preparation; hydrogels; containing; acrylamide-functionalized; carbohydrate; sulfoxide; sulfide; sulfone; copolymerized; hydrophilic; hydrophobic; copolymerizing; material; selected; consisting; acrylamide; methacrylamide; acrylate; methacrylate; vinyl; derivative; concentration; 99; wt; method; fabrication; soft; contact; lenses; biomedical; implants; material selected; hydrogel materials; biomimetic hydrogel; /523/524/526/

Citation Formats


                    Bertozzi, Carolyn, Mukkamala, Ravindranath, Chen, Qing, Hu, Hopin, and Baude, Dominique. Biomimetic hydrogel materials.  United States: N. p., 2000. 
        Web.

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                    Bertozzi, Carolyn, Mukkamala, Ravindranath, Chen, Qing, Hu, Hopin, & Baude, Dominique. Biomimetic hydrogel materials.  United States.

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                    Bertozzi, Carolyn, Mukkamala, Ravindranath, Chen, Qing, Hu, Hopin, and Baude, Dominique. Sat .  
        "Biomimetic hydrogel materials".  United States.  https://www.osti.gov/servlets/purl/873177.

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@article{osti_873177,

  title        = {Biomimetic hydrogel materials},

  author       = {Bertozzi, Carolyn and Mukkamala, Ravindranath and Chen, Qing and Hu, Hopin and Baude, Dominique},

  abstractNote = {Novel biomimetic hydrogel materials and methods for their preparation. Hydrogels containing acrylamide-functionalized carbohydrate, sulfoxide, sulfide or sulfone copolymerized with a hydrophilic or hydrophobic copolymerizing material selected from the group consisting of an acrylamide, methacrylamide, acrylate, methacrylate, vinyl and a derivative thereof present in concentration from about 1 to about 99 wt %. and methods for their preparation. The method of use of the new hydrogels for fabrication of soft contact lenses and biomedical implants.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2000},

  month        = {1}

}

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Works referenced in this record:

Specific targeting of the antiviral drug 5-Iodo 2′-deoxyuridine to the parenchymal liver cell using lactosylated poly-L-lysine
journal, January 1994

Biessen, Erik A. L.; Beuting, Diana M.; Vietsch, Helene
Journal of Hepatology, Vol. 21, Issue 5
https://doi.org/10.1016/S0168-8278(94)80243-2

Synthesis of Sulfated Neoglycopolymers: Selective P-Selectin Inhibitors
journal, April 1997

Manning, David D.; Hu, Xin; Beck, Pamela
Journal of the American Chemical Society, Vol. 119, Issue 13
https://doi.org/10.1021/ja964046x

New strategy in glycopolymer syntheses. Preparation of antigenic water-soluble poly(acrylamide-co-p-acrylamidophenyl .beta.-lactoside)
journal, May 1992

Roy, Rene; Tropper, Francois D.; Romanowska, Anna
Bioconjugate Chemistry, Vol. 3, Issue 3
https://doi.org/10.1021/bc00015a009

Inhibition of influenza A virus hemagglutinin and induction of interferon by synthetic sialylated glycoconjugates
journal, March 1991

Gamian, Andrzej; Chomik, Maria; Laferrière, Craig A.
Canadian Journal of Microbiology, Vol. 37, Issue 3
https://doi.org/10.1139/m91-035

Hepatocyte adhesion to carbohydrate-derivatized surfaces. I. Surface topography of the rat hepatic lectin.
journal, October 1991

Weisz, O. A.; Schnaar, R. L.
Journal of Cell Biology, Vol. 115, Issue 2
https://doi.org/10.1083/jcb.115.2.485

On the wettability of poly(2-hydroxyethylmethacrylate)
journal, March 1992

Morra, M.; Occhiello, E.; Garbassi, F.
Journal of Colloid and Interface Science, Vol. 149, Issue 1
https://doi.org/10.1016/0021-9797(92)90393-Z

Synthetic polymeric sialoside inhibitors of influenza virus receptor-binding activity
journal, October 1990

Matrosovich, M. N.; Mochalova, L. V.; Marinina, V. P.
FEBS Letters, Vol. 272, Issue 1-2
https://doi.org/10.1016/0014-5793(90)80486-3

Protein adsorption on a copolymer having pendant monosaccharide groups. Relationship between surface free energy and protein adsorption
journal, November 1994

Miyata, Takashi; Ootsuki, Norihito; Nakamae, Katsuhiko
Macromolecular Chemistry and Physics, Vol. 195, Issue 11
https://doi.org/10.1002/macp.1994.021951107

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Title: Biomimetic hydrogel materials

Abstract

Citation Formats

Specific targeting of the antiviral drug 5-Iodo 2′-deoxyuridine to the parenchymal liver cell using lactosylated poly-L-lysine journal, January 1994

Synthesis of Sulfated Neoglycopolymers: Selective P-Selectin Inhibitors journal, April 1997

New strategy in glycopolymer syntheses. Preparation of antigenic water-soluble poly(acrylamide-co-p-acrylamidophenyl .beta.-lactoside) journal, May 1992

Inhibition of influenza A virus hemagglutinin and induction of interferon by synthetic sialylated glycoconjugates journal, March 1991

Hepatocyte adhesion to carbohydrate-derivatized surfaces. I. Surface topography of the rat hepatic lectin. journal, October 1991

On the wettability of poly(2-hydroxyethylmethacrylate) journal, March 1992

Synthetic polymeric sialoside inhibitors of influenza virus receptor-binding activity journal, October 1990

Protein adsorption on a copolymer having pendant monosaccharide groups. Relationship between surface free energy and protein adsorption journal, November 1994

Specific targeting of the antiviral drug 5-Iodo 2′-deoxyuridine to the parenchymal liver cell using lactosylated poly-L-lysine
journal, January 1994

Synthesis of Sulfated Neoglycopolymers: Selective P-Selectin Inhibitors
journal, April 1997

New strategy in glycopolymer syntheses. Preparation of antigenic water-soluble poly(acrylamide-co-p-acrylamidophenyl .beta.-lactoside)
journal, May 1992

Inhibition of influenza A virus hemagglutinin and induction of interferon by synthetic sialylated glycoconjugates
journal, March 1991

Hepatocyte adhesion to carbohydrate-derivatized surfaces. I. Surface topography of the rat hepatic lectin.
journal, October 1991

On the wettability of poly(2-hydroxyethylmethacrylate)
journal, March 1992

Synthetic polymeric sialoside inhibitors of influenza virus receptor-binding activity
journal, October 1990

Protein adsorption on a copolymer having pendant monosaccharide groups. Relationship between surface free energy and protein adsorption
journal, November 1994