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Title: Microfluidic interconnects

Abstract

A miniature connector for introducing microliter quantities of solutions into microfabricated fluidic devices, and which incorporates a molded ring or seal set into a ferrule cartridge, with or without a compression screw. The fluidic connector, for example, joins standard high pressure liquid chromatography (HPLC) tubing to 1 mm diameter holes in silicon or glass, enabling ml-sized volumes of sample solutions to be merged with .mu.l-sized devices. The connector has many features, including ease of connect and disconnect; a small footprint which enables numerous connectors to be located in a small area; low dead volume; helium leak-tight; and tubing does not twist during connection. Thus the connector enables easy and effective change of microfluidic devices and introduction of different solutions in the devices.

Inventors:
 [1];  [2]
  1. Livermore, CA
  2. Pleasanton, CA
Issue Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
OSTI Identifier:
873924
Patent Number(s):
6273478
Assignee:
Regents of University of California (Oakland, CA)
Patent Classifications (CPCs):
F - MECHANICAL ENGINEERING F15 - FLUID-PRESSURE ACTUATORS F15C - FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16L - PIPES
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
microfluidic; interconnects; miniature; connector; introducing; microliter; quantities; solutions; microfabricated; fluidic; devices; incorporates; molded; seal; set; ferrule; cartridge; compression; screw; example; joins; standard; pressure; liquid; chromatography; hplc; tubing; diameter; holes; silicon; glass; enabling; ml-sized; volumes; sample; merged; l-sized; features; including; ease; connect; disconnect; footprint; enables; numerous; connectors; located; dead; volume; helium; leak-tight; twist; connection; easy; effective; change; introduction; sample solutions; liquid chromatograph; sample solution; dead volume; liquid chromatography; pressure liquid; microfluidic devices; helium leak; miniature connector; microfluidic interconnects; microliter quantities; microfabricated fluidic; diameter holes; fluidic devices; fluidic connector; introducing microliter; joins standard; /285/

Citation Formats

Benett, William J, and Krulevitch, Peter A. Microfluidic interconnects. United States: N. p., 2001. Web.
Benett, William J, & Krulevitch, Peter A. Microfluidic interconnects. United States.
Benett, William J, and Krulevitch, Peter A. Mon . "Microfluidic interconnects". United States. https://www.osti.gov/servlets/purl/873924.
@article{osti_873924,
title = {Microfluidic interconnects},
author = {Benett, William J and Krulevitch, Peter A},
abstractNote = {A miniature connector for introducing microliter quantities of solutions into microfabricated fluidic devices, and which incorporates a molded ring or seal set into a ferrule cartridge, with or without a compression screw. The fluidic connector, for example, joins standard high pressure liquid chromatography (HPLC) tubing to 1 mm diameter holes in silicon or glass, enabling ml-sized volumes of sample solutions to be merged with .mu.l-sized devices. The connector has many features, including ease of connect and disconnect; a small footprint which enables numerous connectors to be located in a small area; low dead volume; helium leak-tight; and tubing does not twist during connection. Thus the connector enables easy and effective change of microfluidic devices and introduction of different solutions in the devices.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2001},
month = {Mon Jan 01 00:00:00 EST 2001}
}