Butanol tolerance in microorganisms
Abstract
Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products from a pyruvate utilizing pathway. Yeast host cells provided herein comprise reduced pyruvate decarboxylase activity and modified adenylate cyclase activity. In embodiments, yeast host cells provided herein comprise resistance to butanol and increased biomass production.
- Inventors:
- Issue Date:
- Research Org.:
- Butamax Advanced Biofuels LLC, Wilmington, DE (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1241024
- Patent Number(s):
- 9273330
- Application Number:
- 14/045,506
- Assignee:
- Butamax Advanced Biofuels LLC (Wilmington, DE)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- AR0000006
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2013 Oct 03
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Bramucci, Michael G., and Nagarajan, Vasantha. Butanol tolerance in microorganisms. United States: N. p., 2016.
Web.
Bramucci, Michael G., & Nagarajan, Vasantha. Butanol tolerance in microorganisms. United States.
Bramucci, Michael G., and Nagarajan, Vasantha. Tue .
"Butanol tolerance in microorganisms". United States. https://www.osti.gov/servlets/purl/1241024.
@article{osti_1241024,
title = {Butanol tolerance in microorganisms},
author = {Bramucci, Michael G. and Nagarajan, Vasantha},
abstractNote = {Provided herein are recombinant yeast host cells and methods for their use for production of fermentation products from a pyruvate utilizing pathway. Yeast host cells provided herein comprise reduced pyruvate decarboxylase activity and modified adenylate cyclase activity. In embodiments, yeast host cells provided herein comprise resistance to butanol and increased biomass production.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 01 00:00:00 EST 2016},
month = {Tue Mar 01 00:00:00 EST 2016}
}
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