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Title: Method for determining properties of red blood cells

Abstract

A method for quantifying the concentration of hemoglobin in a cell, and indicia of anemia, comprises determining the wavelength of the longitudinal mode of a liquid in a laser microcavity; determining the wavelength of the fundamental transverse mode of a red blood cell in the liquid in the laser microcavity; and determining if the cell is anemic from the difference between the wavelength of the longitudinal mode and the fundamental transverse mode. In addition to measuring hemoglobin, the invention includes a method using intracavity laser spectroscopy to measure the change in spectra as a function of time for measuring the influx of water into a red blood cell and the cell's subsequent rupture.

Inventors:
 [1]
  1. Albuquerque, NM
Issue Date:
Research Org.:
SANDIA CORP
OSTI Identifier:
873551
Patent Number(s):
6187592
Assignee:
Sandia Corporation (Albuquerque, NM)
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; determining; properties; blood; cells; quantifying; concentration; hemoglobin; cell; indicia; anemia; comprises; wavelength; longitudinal; mode; liquid; laser; microcavity; fundamental; transverse; anemic; difference; addition; measuring; intracavity; spectroscopy; measure; change; spectra; function; time; influx; water; subsequent; rupture; laser spectroscopy; blood cells; blood cell; longitudinal mode; comprises determining; transverse mode; determining properties; /436/356/

Citation Formats

Gourley, Paul L. Method for determining properties of red blood cells. United States: N. p., 2001. Web.
Gourley, Paul L. Method for determining properties of red blood cells. United States.
Gourley, Paul L. Mon . "Method for determining properties of red blood cells". United States. https://www.osti.gov/servlets/purl/873551.
@article{osti_873551,
title = {Method for determining properties of red blood cells},
author = {Gourley, Paul L},
abstractNote = {A method for quantifying the concentration of hemoglobin in a cell, and indicia of anemia, comprises determining the wavelength of the longitudinal mode of a liquid in a laser microcavity; determining the wavelength of the fundamental transverse mode of a red blood cell in the liquid in the laser microcavity; and determining if the cell is anemic from the difference between the wavelength of the longitudinal mode and the fundamental transverse mode. In addition to measuring hemoglobin, the invention includes a method using intracavity laser spectroscopy to measure the change in spectra as a function of time for measuring the influx of water into a red blood cell and the cell's subsequent rupture.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2001},
month = {1}
}

Patent:

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