Method for determining properties of red blood cells
Abstract
A method for quantifying the concentration of hemoglobin in a cell, and indicia of anemia, comprises determining the wavelength of the longitudinal mode of a liquid in a laser microcavity; determining the wavelength of the fundamental transverse mode of a red blood cell in the liquid in the laser microcavity; and determining if the cell is anemic from the difference between the wavelength of the longitudinal mode and the fundamental transverse mode. In addition to measuring hemoglobin, the invention includes a method using intracavity laser spectroscopy to measure the change in spectra as a function of time for measuring the influx of water into a red blood cell and the cell's subsequent rupture.
- Inventors:
-
- Albuquerque, NM
- Issue Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- OSTI Identifier:
- 873551
- Patent Number(s):
- 6187592
- Assignee:
- Sandia Corporation (Albuquerque, NM)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- method; determining; properties; blood; cells; quantifying; concentration; hemoglobin; cell; indicia; anemia; comprises; wavelength; longitudinal; mode; liquid; laser; microcavity; fundamental; transverse; anemic; difference; addition; measuring; intracavity; spectroscopy; measure; change; spectra; function; time; influx; water; subsequent; rupture; laser spectroscopy; blood cells; blood cell; longitudinal mode; comprises determining; transverse mode; determining properties; /436/356/
Citation Formats
Gourley, Paul L. Method for determining properties of red blood cells. United States: N. p., 2001.
Web.
Gourley, Paul L. Method for determining properties of red blood cells. United States.
Gourley, Paul L. Mon .
"Method for determining properties of red blood cells". United States. https://www.osti.gov/servlets/purl/873551.
@article{osti_873551,
title = {Method for determining properties of red blood cells},
author = {Gourley, Paul L},
abstractNote = {A method for quantifying the concentration of hemoglobin in a cell, and indicia of anemia, comprises determining the wavelength of the longitudinal mode of a liquid in a laser microcavity; determining the wavelength of the fundamental transverse mode of a red blood cell in the liquid in the laser microcavity; and determining if the cell is anemic from the difference between the wavelength of the longitudinal mode and the fundamental transverse mode. In addition to measuring hemoglobin, the invention includes a method using intracavity laser spectroscopy to measure the change in spectra as a function of time for measuring the influx of water into a red blood cell and the cell's subsequent rupture.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2001},
month = {1}
}
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