Triamine chelants, their derivatives, complexes and conjugates
Abstract
A group of functionalized triamine chelants and their derivatives that form complexes with radioactive metal ions are disclosed. The complexes can be covalently attached to a protein or an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. The chelants are of the formula: ##STR1## wherein n, m, R, R.sup.1, R.sup.2 and L are defined in the specification.
- Inventors:
-
- Phoenixville, PA
- Gaithersburg, MD
- Vashi, IN
- Issue Date:
- Research Org.:
- Univ. of Missouri, Columbia, MO (United States)
- OSTI Identifier:
- 869774
- Patent Number(s):
- 5395608
- Assignee:
- Curators of University of Missouri (Columbia, MO)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
- DOE Contract Number:
- FG02-86ER60400
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- triamine; chelants; derivatives; complexes; conjugates; functionalized; form; radioactive; metal; disclosed; covalently; attached; protein; antibody; fragment; therapeutic; diagnostic; purposes; formula; str1; defined; specification; radioactive metal; active metal; triamine chelants; antibody fragment; diagnostic purposes; covalently attached; functionalized triamine; form complexes; /424/530/999/
Citation Formats
Troutner, David E, John, Christy S, and Pillai, Maroor R. A. Triamine chelants, their derivatives, complexes and conjugates. United States: N. p., 1995.
Web.
Troutner, David E, John, Christy S, & Pillai, Maroor R. A. Triamine chelants, their derivatives, complexes and conjugates. United States.
Troutner, David E, John, Christy S, and Pillai, Maroor R. A. Sun .
"Triamine chelants, their derivatives, complexes and conjugates". United States. https://www.osti.gov/servlets/purl/869774.
@article{osti_869774,
title = {Triamine chelants, their derivatives, complexes and conjugates},
author = {Troutner, David E and John, Christy S and Pillai, Maroor R. A.},
abstractNote = {A group of functionalized triamine chelants and their derivatives that form complexes with radioactive metal ions are disclosed. The complexes can be covalently attached to a protein or an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. The chelants are of the formula: ##STR1## wherein n, m, R, R.sup.1, R.sup.2 and L are defined in the specification.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sun Jan 01 00:00:00 EST 1995},
month = {Sun Jan 01 00:00:00 EST 1995}
}
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