Triamine chelants, their derivatives, complexes and conjugates
Abstract
A group of functionalized triamine chelants and their derivatives that form complexes with radioactive metal ions are disclosed. The complexes can be covalently attached to a protein or an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. The chelants are of the formula, as shown in the accompanying diagrams, wherein n, m, R, R{sup 1}, R{sup 2} and L are defined in the specification.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of Missouri, Columbia, MO (United States)
- OSTI Identifier:
- 27713
- Patent Number(s):
- 5395608
- Application Number:
- PAN: 7-697,861
- Assignee:
- Univ. of Missouri, Columbia, MO (United States)
- DOE Contract Number:
- FG02-86ER60400
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 7 Mar 1995
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; RADIOPHARMACEUTICALS; CHEMICAL PREPARATION; CHELATING AGENTS; THERAPEUTIC USES; DIAGNOSTIC USES; NUCLEAR MEDICINE
Citation Formats
Troutner, D E, John, C S, and Pillai, M R.A. Triamine chelants, their derivatives, complexes and conjugates. United States: N. p., 1995.
Web.
Troutner, D E, John, C S, & Pillai, M R.A. Triamine chelants, their derivatives, complexes and conjugates. United States.
Troutner, D E, John, C S, and Pillai, M R.A. Tue .
"Triamine chelants, their derivatives, complexes and conjugates". United States.
@article{osti_27713,
title = {Triamine chelants, their derivatives, complexes and conjugates},
author = {Troutner, D E and John, C S and Pillai, M R.A.},
abstractNote = {A group of functionalized triamine chelants and their derivatives that form complexes with radioactive metal ions are disclosed. The complexes can be covalently attached to a protein or an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. The chelants are of the formula, as shown in the accompanying diagrams, wherein n, m, R, R{sup 1}, R{sup 2} and L are defined in the specification.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {3}
}