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Title: Hydroxyalkyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals

Abstract

This research discloses a compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises a functionalized hydroxyalkyl phosphine ligand and a metal combined with the ligand. 16 figs.

Inventors:
; ; ; ; ;
Issue Date:
Research Org.:
Univ. of Missouri, Columbia, MO (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
335471
Patent Number(s):
5876693
Application Number:
PAN: 8-902,829
Assignee:
Univ. of Missouri, Columbia, MO (United States)
DOE Contract Number:  
FG02-89ER60875
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 2 Mar 1999
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; LIGANDS; PHOSPHINES; CHEMICAL PREPARATION; USES; METALS; DRUGS

Citation Formats

Katti, K V, Singh, P R, Reddy, V S, Katti, K K, Volkert, W A, and Ketring, A R. Hydroxyalkyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals. United States: N. p., 1999. Web.
Katti, K V, Singh, P R, Reddy, V S, Katti, K K, Volkert, W A, & Ketring, A R. Hydroxyalkyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals. United States.
Katti, K V, Singh, P R, Reddy, V S, Katti, K K, Volkert, W A, and Ketring, A R. Tue . "Hydroxyalkyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals". United States.
@article{osti_335471,
title = {Hydroxyalkyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals},
author = {Katti, K V and Singh, P R and Reddy, V S and Katti, K K and Volkert, W A and Ketring, A R},
abstractNote = {This research discloses a compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises a functionalized hydroxyalkyl phosphine ligand and a metal combined with the ligand. 16 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 02 00:00:00 EST 1999},
month = {Tue Mar 02 00:00:00 EST 1999}
}

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Works referenced in this record:

Synthesis and crystal and molecular structure of a technetium-hydralazino complex, [TcCl2(C8H5N4)(PPh3)2]·0.75C7H8
journal, July 1990


Aspects of the Chemistry of Technetium Phosphine Complexes
journal, January 1993


Coordination compounds in nuclear medicine
journal, May 1993


Water-soluble tris(hydroxymethyl)phosphine complexes with nickel, palladium, and platinum. Crystal structure of [Pd{P(CH2OH)3}4].cntdot.CH3
journal, July 1992


Specific and stable labeling of antibodies with technetium-99m with a diamide dithiolate chelating agent.
journal, June 1988


Synthesis of a new class of Tc chelating agents: N2S2 monoaminemonoamide (mama) ligands
journal, September 1991


Tumour targeting with radiolabelled macrocycle–antibody conjugates
journal, January 1990


Chelate radiochemistry: Cleavable linkers lead to altered levels of radioactivity in the liver
journal, January 1988


Kinetics and mechanism of reactions of S-protected dithiol monoaminemonoamide (MAMA) ligands with technetium: Characterization of a technetium—thiolate—thioether—MAMA complex, a kinetic intermediate of the reaction
journal, November 1992

  • Rao, T. N.; Gustavson, Linda M.; Srinivasan, Ananthachari
  • International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, Vol. 19, Issue 8
  • https://doi.org/10.1016/0883-2897(92)90175-X

Chemical and physical properties of radionuclides
journal, January 1987