Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same
Abstract
A complex and method for making a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids. 20 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of Missouri, Columbia, MO (United States)
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 321196
- Patent Number(s):
- 5843993
- Application Number:
- PAN: 8-818,078; TRN: 99:003302
- Assignee:
- Univ. of Missouri, Columbia, MO (United States)
- DOE Contract Number:
- FG02-89ER60875
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 1 Dec 1998
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; 40 CHEMISTRY; DIAGNOSTIC USES; THERAPEUTIC USES; LIGANDS; RADIOPHARMACEUTICALS; GOLD; COMPLEXES; PHOSPHINES
Citation Formats
Katti, K V, Berning, D E, Volkert, W A, and Ketring, A R. Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same. United States: N. p., 1998.
Web.
Katti, K V, Berning, D E, Volkert, W A, & Ketring, A R. Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same. United States.
Katti, K V, Berning, D E, Volkert, W A, and Ketring, A R. Tue .
"Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same". United States.
@article{osti_321196,
title = {Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same},
author = {Katti, K V and Berning, D E and Volkert, W A and Ketring, A R},
abstractNote = {A complex and method for making a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids. 20 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {12}
}
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