Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same
Abstract
A complex and method for making same for use as a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids.
- Inventors:
-
- Columbia, MO
- Issue Date:
- Research Org.:
- Univ. of Missouri, Columbia, MO (United States)
- OSTI Identifier:
- 872011
- Patent Number(s):
- 5843993
- Assignee:
- Curators of University of Missouri (Columbia, MO)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07F - ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- DOE Contract Number:
- FG02-89ER60875
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- hydroxyalkyl; phosphine; gold; complexes; diagnostic; therapeutic; pharmaceuticals; method; complex; pharmaceutical; ligand; comprising; donor; bound; atom; form; gold-ligand; stable; aqueous; solutions; containing; oxygen; serum; fluids; therapeutic pharmaceutical; hydroxyalkyl phosphine; aqueous solution; aqueous solutions; solutions containing; containing oxygen; phosphine donor; therapeutic pharmaceuticals; ligand comprising; ligand complex; /514/999/
Citation Formats
Katti, Kattesh V, Berning, Douglas E, Volkert, Wynn A, and Ketring, Alan R. Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same. United States: N. p., 1998.
Web.
Katti, Kattesh V, Berning, Douglas E, Volkert, Wynn A, & Ketring, Alan R. Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same. United States.
Katti, Kattesh V, Berning, Douglas E, Volkert, Wynn A, and Ketring, Alan R. Thu .
"Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same". United States. https://www.osti.gov/servlets/purl/872011.
@article{osti_872011,
title = {Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same},
author = {Katti, Kattesh V and Berning, Douglas E and Volkert, Wynn A and Ketring, Alan R},
abstractNote = {A complex and method for making same for use as a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}
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