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Title: Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same

Abstract

A complex and method for making same for use as a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids.

Inventors:
 [1];  [1];  [1];  [1]
  1. (Columbia, MO)
Issue Date:
Research Org.:
University of Missouri
OSTI Identifier:
872011
Patent Number(s):
5843993
Assignee:
Curators of University of Missouri (Columbia, MO) CHO
DOE Contract Number:  
FG02-89ER60875
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
hydroxyalkyl; phosphine; gold; complexes; diagnostic; therapeutic; pharmaceuticals; method; complex; pharmaceutical; ligand; comprising; donor; bound; atom; form; gold-ligand; stable; aqueous; solutions; containing; oxygen; serum; fluids; therapeutic pharmaceutical; hydroxyalkyl phosphine; aqueous solution; aqueous solutions; solutions containing; containing oxygen; phosphine donor; therapeutic pharmaceuticals; ligand comprising; ligand complex; /514/999/

Citation Formats

Katti, Kattesh V., Berning, Douglas E., Volkert, Wynn A., and Ketring, Alan R. Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same. United States: N. p., 1998. Web.
Katti, Kattesh V., Berning, Douglas E., Volkert, Wynn A., & Ketring, Alan R. Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same. United States.
Katti, Kattesh V., Berning, Douglas E., Volkert, Wynn A., and Ketring, Alan R. Thu . "Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same". United States. https://www.osti.gov/servlets/purl/872011.
@article{osti_872011,
title = {Hydroxyalkyl phosphine gold complexes for use as diagnostic and therapeutic pharmaceuticals and method of making same},
author = {Katti, Kattesh V. and Berning, Douglas E. and Volkert, Wynn A. and Ketring, Alan R.},
abstractNote = {A complex and method for making same for use as a diagnostic or therapeutic pharmaceutical includes a ligand comprising at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a gold-ligand complex that is stable in aqueous solutions containing oxygen, serum and other body fluids.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}

Patent:

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