Over-expression of AZF1 improves the rate of anaerobic xylose fermentation in engineered yeast strains

Gasch, Audrey P.; Myers, Kevin

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Title: Over-expression of AZF1 improves the rate of anaerobic xylose fermentation in engineered yeast strains

Abstract

The present invention provides an isolated AZF1 gene sequence, recombinant vectors, and recombinant yeast which are useful in methods of enhanced biofuel production, particularly ethanol production. Methods of bioengineering recombinant yeast with isolated AZF1 gene sequence useful for biofuel production are also provided.

Inventors:: Gasch, Audrey P.; Myers, Kevin

Issue Date:: Tue Feb 28 00:00:00 EST 2023

Research Org.:: Univ. of Wisconsin, Madison, WI (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1987170

Patent Number(s):: 11591376

Application Number:: 16/156,463

Assignee:: Wisconsin Alumni Research Foundation (Madison, WI)

DOE Contract Number:: FC02-07ER64494

Resource Type:: Patent

Resource Relation:: Patent File Date: 10/10/2018

Country of Publication:: United States

Language:: English

Citation Formats


                    Gasch, Audrey P., and Myers, Kevin. Over-expression of AZF1 improves the rate of anaerobic xylose fermentation in engineered yeast strains.  United States: N. p., 2023. 
        Web.

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                    Gasch, Audrey P., & Myers, Kevin. Over-expression of AZF1 improves the rate of anaerobic xylose fermentation in engineered yeast strains.  United States.

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                    Gasch, Audrey P., and Myers, Kevin. Tue .  
        "Over-expression of AZF1 improves the rate of anaerobic xylose fermentation in engineered yeast strains".  United States.  https://www.osti.gov/servlets/purl/1987170.

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@article{osti_1987170,

  title        = {Over-expression of AZF1 improves the rate of anaerobic xylose fermentation in engineered yeast strains},

  author       = {Gasch, Audrey P. and Myers, Kevin},

  abstractNote = {The present invention provides an isolated AZF1 gene sequence, recombinant vectors, and recombinant yeast which are useful in methods of enhanced biofuel production, particularly ethanol production. Methods of bioengineering recombinant yeast with isolated AZF1 gene sequence useful for biofuel production are also provided.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Feb 28 00:00:00 EST 2023},

  month        = {Tue Feb 28 00:00:00 EST 2023}

}

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Works referenced in this record:

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Similar Records

Title: Over-expression of AZF1 improves the rate of anaerobic xylose fermentation in engineered yeast strains

Abstract

Citation Formats

Xylose Assimilation for the Efficient Production of Biofuels and Chemicals by Engineered Saccharomyces cerevisiae journal, November 2020

Rewired cellular signaling coordinates sugar and hypoxic responses for anaerobic xylose fermentation in yeast journal, March 2019

Methods for Improving Secondary Metabolite Production of Fungi patent-application, November 2006

AZF1 Is a Glucose-Dependent Positive Regulator of CLN3 Transcription in Saccharomyces cerevisiae journal, March 2002

Galactosyltransferase patent-application, February 2010

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A new nuclear suppressor system for a mitochondrial RNA polymerase mutant identifies an unusual zinc‐finger protein and a polyglutamine domain protein in Saccharomyces cerevisiae journal, June 1994

Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins journal, February 2013

High expression of XYL2 coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered Saccharomyces cerevisiae journal, July 2012

Luminescent nitrifying microorganisms patent, May 1999

Yeast/E. coli shuttle vectors with multiple unique restriction sites journal, September 1986

The Function and Properties of the Azf1 Transcriptional Regulator Change with Growth Conditions in Saccharomyces cerevisiae journal, February 2006

Xylose isomerase overexpression along with engineering of the pentose phosphate pathway and evolutionary engineering enable rapid xylose utilization and ethanol production by Saccharomyces cerevisiae journal, November 2012

Bacterial Xylose Isomerases Active in Yeast Cells patent-application, May 2016

Transcriptional Profiling of Biofilm Regulators Identified by an Overexpression Screen in Saccharomyces cerevisiae journal, August 2017

A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds journal, April 2009

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Kinetic modelling reveals current limitations in the production of ethanol from xylose by recombinant Saccharomyces cerevisiae journal, September 2011

Methods of increasing accumulation of essential amino acids in seeds patent, October 2000

Correlation between microarray DNA hybridization efficiency and the position of short capture probe on the target nucleic acid journal, July 2005

Systematic Genomic Library and Uses Thereof patent-application, November 2010

Metabolic engineering of a xylose-isomerase-expressing strain for rapid anaerobic xylose fermentation journal, February 2005

Xylose Assimilation for the Efficient Production of Biofuels and Chemicals by Engineered Saccharomyces cerevisiae
journal, November 2020

Rewired cellular signaling coordinates sugar and hypoxic responses for anaerobic xylose fermentation in yeast
journal, March 2019

Methods for Improving Secondary Metabolite Production of Fungi
patent-application, November 2006

AZF1 Is a Glucose-Dependent Positive Regulator of CLN3 Transcription in Saccharomyces cerevisiae
journal, March 2002

Galactosyltransferase
patent-application, February 2010

Codon Optimization of a Synthetic Gene(s) for Protein Expression
patent-application, August 2014

A new nuclear suppressor system for a mitochondrial RNA polymerase mutant identifies an unusual zinc‐finger protein and a polyglutamine domain protein in Saccharomyces cerevisiae
journal, June 1994

Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins
journal, February 2013

High expression of XYL2 coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered Saccharomyces cerevisiae
journal, July 2012

Luminescent nitrifying microorganisms
patent, May 1999

Yeast/E. coli shuttle vectors with multiple unique restriction sites
journal, September 1986

The Function and Properties of the Azf1 Transcriptional Regulator Change with Growth Conditions in Saccharomyces cerevisiae
journal, February 2006

Xylose isomerase overexpression along with engineering of the pentose phosphate pathway and evolutionary engineering enable rapid xylose utilization and ethanol production by Saccharomyces cerevisiae
journal, November 2012

Bacterial Xylose Isomerases Active in Yeast Cells
patent-application, May 2016

Transcriptional Profiling of Biofilm Regulators Identified by an Overexpression Screen in Saccharomyces cerevisiae
journal, August 2017

A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds
journal, April 2009

Method for the Production of Transgenic Plants with Increased Virus Resistance by Silencing Vegetable DNAJ-Like Proteins
patent-application, November 2005

Kinetic modelling reveals current limitations in the production of ethanol from xylose by recombinant Saccharomyces cerevisiae
journal, September 2011

Methods of increasing accumulation of essential amino acids in seeds
patent, October 2000

Correlation between microarray DNA hybridization efficiency and the position of short capture probe on the target nucleic acid
journal, July 2005

Systematic Genomic Library and Uses Thereof
patent-application, November 2010

Metabolic engineering of a xylose-isomerase-expressing strain for rapid anaerobic xylose fermentation
journal, February 2005