Disruption of the cytochrome C gene in xylose-fermenting yeast

Jeffries, Thomas W.; Shi, Nian-Qing

Title: Disruption of the cytochrome C gene in xylose-fermenting yeast

Patent · Tue Jun 06 00:00:00 EDT 2000

OSTI ID:1531428

Jeffries, Thomas W.; Shi, Nian-Qing

Disclosed is a xylose-fermenting mutant yeast strain exhibiting reduced expression of cytochrome c and enhanced fermentation of xylose relative to xylose-fermenting yeast strains in which cytochrome c is fully functional. Also disclosed is a method of producing ethanol from xylose by culturing a xylose-fermenting mutant yeast strain exhibiting reduced expression of cytochrome c in the presence of xylose-containing material.

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Research Organization:: National Renewable Energy Laboratory (NREL), Golden, CO (United States); The Consortium for Plant Biotechnology Research, Inc.

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-83CH10093; FC05-92OR22072; HG0301; PA0 USDA

Assignee:: Jeffries, Thomas W., Madison, WI (United States)

Patent Number(s):: 6,071,729

Application Number:: 09/274,642

OSTI ID:: 1531428

Resource Relation:: Patent File Date: 1999-03-23

Country of Publication:: United States

Language:: English

References (4)

Diminished Respirative Growth and Enhanced Assimilative Sugar Uptake Result in Higher Specific Fermentation Rates by the Mutant Pichia stipitis FPL-061 Sreenath, Hassan K.; Jeffries, Thomas W. Biotechnology for Fuels and Chemicals https://doi.org/10.1007/978-1-4612-2312-2_11	book	January 1997
Xylose-fermenting yeast mutants Jeffries, Thomas W.; Livingston, Philip https://doi.org/https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5126266 US Patent Document 5,126,266	patent	June 1992
Cloning and disruption of the b-isopropylmalate dehydrogenase gene ( LEU2 ) of Pichia stipitis with URA3 and recovery of the double auxotroph Lu, P.; Davis, B. P.; Hendrick, J. Applied Microbiology and Biotechnology, Vol. 49, Issue 2 https://doi.org/10.1007/s002530051150	journal	February 1998
Existence of Cyanide-Insensitive Respiration in the Yeast Pichia stipitis and Its Possible Influence on Product Formation during Xylose Utilization. Jeppsson, H.; Alexander, N. J.; Hahn-Hagerdal, B. Applied and environmental microbiology, Vol. 61, Issue 7 https://doi.org/10.1128/AEM.61.7.2596-2600.1995	journal	January 1995

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