Antigenic combinations against Francisella bacteria and related nanolipoprotein particles, compositions, methods and systems
Abstract
Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States); Univ. of New Mexico, Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1986801
- Patent Number(s):
- 11491215
- Application Number:
- 16/543,463
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA); Regents of the University of New Mexico (Albuquerque, NM)
- DOE Contract Number:
- AC52-07NA27344
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 08/16/2019
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Fischer, Nicholas, Rasley, Amy, Wu, Terry, and Lovchik, Julie A. Antigenic combinations against Francisella bacteria and related nanolipoprotein particles, compositions, methods and systems. United States: N. p., 2022.
Web.
Fischer, Nicholas, Rasley, Amy, Wu, Terry, & Lovchik, Julie A. Antigenic combinations against Francisella bacteria and related nanolipoprotein particles, compositions, methods and systems. United States.
Fischer, Nicholas, Rasley, Amy, Wu, Terry, and Lovchik, Julie A. Tue .
"Antigenic combinations against Francisella bacteria and related nanolipoprotein particles, compositions, methods and systems". United States. https://www.osti.gov/servlets/purl/1986801.
@article{osti_1986801,
title = {Antigenic combinations against Francisella bacteria and related nanolipoprotein particles, compositions, methods and systems},
author = {Fischer, Nicholas and Rasley, Amy and Wu, Terry and Lovchik, Julie A.},
abstractNote = {Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2022},
month = {11}
}
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